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麻风病与美洲皮肤利什曼病合并感染。

Leprosy and American cutaneous leishmaniasis coinfection.

作者信息

Mercadante Larissa Mondadori, Santos Marcel Alex Soares Dos, Pegas Elisangela Samartin, Kadunc Bogdana Victória

机构信息

Dermatology Service at Pontifícia Universidade Católica de Campinas (PUC - Campinas) - Campinas (SP), Brazil.

Leprosy Outpatient Service at Pontifícia Universidade Católica de Campinas (PUC - Campinas) - Campinas (SP), Brazil.

出版信息

An Bras Dermatol. 2018 Jan-Feb;93(1):123-125. doi: 10.1590/abd1806-4841.20186698.

Abstract

Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen.

摘要

巴西是一个麻风病和利什曼病等传染病高发的国家。然而,这些疾病的合并感染仍未得到充分了解。我们报告了一例同时患有瘤型麻风病和皮肤黏膜利什曼病的患者。经过临床、实验室和组织病理学诊断后,开始进行治疗,患者临床症状有显著改善。他在我们的门诊接受随访。这两种病症在免疫系统中都起着重要作用。根据宿主的免疫反应情况,疾病可能会以不同方式表现出来。在这个病例中,患者对每种疾病都表现出不同的免疫反应。我们推测这种反应对每种病原体都是特异性的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77d8/5871378/246c18836177/abd-93-01-0123-g01.jpg

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