精油及其主要成分对恰加斯病传播媒介的作用

Essential Oils and Their Major Components against , a Vector of Chagas Disease.

作者信息

de Souza Thamiris de A, Lopes Marcio B P, Ramos Aline de S, Ferreira José Luiz P, Silva Jefferson Rocha de A, Queiroz Margareth M C, Araújo Kátia G de Lima, Amaral Ana Claudia F

机构信息

Faculty of Pharmacy, Federal Fluminense University, Rua Doutor Mário Viana 523, Santa Rosa, Niterói, RJ, Brazil.

Laboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, FIOCRUZ, Rio de Janeiro, RJ, Brazil.

出版信息

ScientificWorldJournal. 2018 Feb 15;2018:2393858. doi: 10.1155/2018/2393858. eCollection 2018.

DOI:10.1155/2018/2393858

PMID:29643755

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5832174/

Abstract

Species of the genus are widely used by the population and have many described biological activities, including activity against insects. In this paper, we describe the bioactivity of the essential oil of two species of genus, and , against , a vector of Chagas disease. The essential oils of these two species were obtained by hydrodistillation and analyzed by GC-MS. The main constituent of essential oil (OLALPZER) was terpinen-4-ol, which represented 19.7% of the total components identified. In the essential oil of (OLALPVIT) the monoterpene -pinene (35.3%) was the main constituent. The essential oils and their main constituents were topically applied on fifth-instar nymphs. In the first 10 min of application, OLALPVIT and OLALPZER at 125 g/mL provoked 73.3% and 83.3% of mortality, respectively. Terpinen-4-ol at 25 g/mL and -pinene at 44 g/mL provoked 100% of mortality. The monitoring of resistant insects showed that both essential oils exhibited antifeedant activity. These results suggest the potential use of and essential oils and their major constituents to control population.

摘要

该属的物种被人们广泛使用，并且具有许多已描述的生物活性，包括对昆虫的活性。在本文中，我们描述了该属两种物种（[物种名称1]和[物种名称2]）的精油对恰加斯病传播媒介[昆虫名称]的生物活性。这两种物种的精油通过水蒸馏法获得，并通过气相色谱 - 质谱联用仪进行分析。[物种名称1]精油（OLALPZER）的主要成分是萜品 - 4 - 醇，占已鉴定总成分的19.7%。在[物种名称2]的精油（OLALPVIT）中，单萜α - 蒎烯（35.3%）是主要成分。将精油及其主要成分局部施用于[昆虫名称]的五龄若虫。在施用的前10分钟内，浓度为125μg/mL的OLALPVIT和OLALPZER分别引起73.3%和83.3%的死亡率。浓度为25μg/mL的萜品 - 4 - 醇和44μg/mL的α - 蒎烯引起100%的死亡率。对抗性昆虫的监测表明，这两种精油均表现出拒食活性。这些结果表明[物种名称1]和[物种名称2]的精油及其主要成分在控制[昆虫名称]种群方面具有潜在用途。