Department of Public Health, School of Health Sciences and Practice, New York Medical College, Valhalla.
School of Biological and Population Health Sciences, Oregon State University, Corvallis.
J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):575-581. doi: 10.1093/gerona/gly080.
Disability in activities of daily living (ADLs) is a dynamic process and transitions among different disability states are common. However, little is known about factors affecting recovery from disability. We examined the association between frailty and recovery from disability among nondisabled community-dwelling elders.
We studied 1,023 adults from the Cardiovascular Health Study (CHS) and 685 adults from the Health and Retirement Study (HRS), who were ≥65 years and had incident disability, defined as having difficulty in ≥1 ADL (dressing, eating, toileting, bathing, transferring, walking across a room). Disability recovery was defined as having no difficulty in any ADLs. Frailty was assessed by slowness, weakness, exhaustion, inactivity, and shrinking. Persons were classified as "nonfrail" (0 criteria), "prefrail" (1-2 criteria), or "frail" (3-5 criteria).
In total, 539 (52.7%) CHS participants recovered from disability within 1 year. Almost two-thirds of nonfrail persons recovered, while less than two-fifths of the frail recovered. In the HRS, 234 (34.2%) participants recovered from disability within 2 years. Approximately half of the nonfrail recovered, while less than one-fifth of the frail recovered. After adjustment, prefrail and frail CHS participants were 16% and 36% less likely to recover than the nonfrail, respectively. In the HRS, frail persons had a 41% lower likelihood of recovery than the nonfrail.
Frailty is an independent predictor of poor recovery from disability among nondisabled older adults. These findings validate frailty as a marker of decreased resilience and may offer opportunities for individualized interventions and geriatric care based on frailty assessment.
日常生活活动(ADL)障碍是一个动态过程,不同残疾状态之间的转变是常见的。然而,人们对影响残疾恢复的因素知之甚少。我们研究了非残疾社区居住的老年人中衰弱与残疾恢复之间的关系。
我们研究了心血管健康研究(CHS)中的 1023 名成年人和健康与退休研究(HRS)中的 685 名成年人,他们年龄均≥65 岁,且患有新发残疾,定义为在≥1 项 ADL(穿衣、进食、如厕、洗澡、转移、穿过房间行走)方面存在困难。残疾恢复定义为在任何 ADL 方面均无困难。衰弱通过缓慢、虚弱、疲惫、不活动和消瘦来评估。将个体分为“非衰弱”(无 0 项标准)、“衰弱前期”(有 1-2 项标准)或“衰弱”(有 3-5 项标准)。
在 CHS 中,共有 539 名(52.7%)参与者在 1 年内从残疾中恢复。近三分之二的非衰弱者恢复,而不到五分之二的衰弱者恢复。在 HRS 中,有 234 名(34.2%)参与者在 2 年内从残疾中恢复。大约一半的非衰弱者恢复,而不到五分之一的衰弱者恢复。调整后,衰弱前期和衰弱的 CHS 参与者分别比非衰弱者恢复的可能性低 16%和 36%。在 HRS 中,衰弱者恢复的可能性比非衰弱者低 41%。
衰弱是无残疾老年人大脑残疾恢复不良的独立预测因素。这些发现验证了衰弱是弹性降低的标志,可能为基于衰弱评估的个体化干预和老年医学提供机会。