Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Cell Host Microbe. 2018 Apr 11;23(4):432-434. doi: 10.1016/j.chom.2018.03.018.
Chronic nonhealing wounds represent a significant clinical problem and cost the healthcare system $19 billion annually. Recently, Vågesjö et al. (2018) demonstrated a promising therapeutic approach for nonhealing wounds with topical application of CXCL12-producing Lactobacilli that enhanced healing through alterations in the wound microenvironment.
慢性难愈性创面是一个重大的临床问题,每年给医疗系统造成 190 亿美元的损失。最近,Vågesjö 等人(2018 年)通过局部应用产生 CXCL12 的乳杆菌为慢性难愈性创面提供了一种很有前景的治疗方法,该方法通过改变创面微环境来促进创面愈合。