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面对吗啡、氢吗啡酮和芬太尼短缺的情况该使用何种胃肠外阿片类药物。

What Parenteral Opioids to Use in Face of Shortages of Morphine, Hydromorphone, and Fentanyl.

作者信息

Davis Mellar P, McPherson Mary Lynn, Mehta Zankhana, Behm Bertrand, Fernandez Carlos

机构信息

1 Department of Palliative Care, Geisinger Medical Center, Danville, PA, USA.

2 Advanced Post-Graduate Education in Palliative Care, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, MD, USA.

出版信息

Am J Hosp Palliat Care. 2018 Aug;35(8):1118-1122. doi: 10.1177/1049909118771374. Epub 2018 Apr 12.

DOI:10.1177/1049909118771374
PMID:29649890
Abstract

Parenteral potent opioid availability is becoming an issue in acute pain management. Two opioids, nalbuphine and buprenorphine, are available which can be substituted for hydromorphone, fentanyl, and morphine. There are advantages and disadvantages in using these 2 opioids which are discussed, and potential dosing strategies are outlined.

摘要

胃肠外强效阿片类药物的可获得性正成为急性疼痛管理中的一个问题。有两种阿片类药物，纳布啡和丁丙诺啡，可以替代氢吗啡酮、芬太尼和吗啡。本文讨论了使用这两种阿片类药物的优缺点，并概述了潜在的给药策略。

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