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肝移植受者的自我管理:一项叙述性综述

Self-Management in Liver Transplant Recipients: A Narrative Review.

作者信息

Ko Dami, Muehrer Rebecca J, Bratzke Lisa C

机构信息

1 School of Nursing, University of Wisconsin-Madison, Madison, WI, USA.

出版信息

Prog Transplant. 2018 Jun;28(2):100-115. doi: 10.1177/1526924818765814. Epub 2018 Apr 12.

DOI:10.1177/1526924818765814
PMID:29649931
Abstract

INTRODUCTION

Although self-management is essential for liver transplant recipients, there is no review that has synthesized findings related to self-management in this population.

OBJECTIVE

This narrative review aimed to synthesize the current findings and identify the gaps in knowledge about self-management in liver recipients.

METHODS

A search of PubMed, CINAHL Plus, PsychINFO, ProQuest, and Web of Science was conducted using the following terms: [Self-care OR Self-management OR Health behavior] AND [Liver transplantation]. Peer-reviewed published research articles focusing on self-management of adult recipients were selected. A total of 23 articles were included for review. Two reviewers independently reviewed the full text of selected articles and extracted the data about definitions, measurements, and findings regarding self-management.

RESULTS

Three areas of self-management were identified, including medication nonadherence (n = 11), alcohol recidivism (n = 11), and health maintenance (n = 5). Reported rates of medication nonadherence ranged from 8% to 66%. Medication nonadherence was related to recipients' demographic (eg, age or sex), transplant-related (eg, time since transplant), and pretransplant variables (eg, history of substance/alcohol abuse). Reported alcohol recidivism rates ranged from 3% to 95%. Age, pretransplant variables (eg, abstinent time before transplant), and personality disorder were identified to be related to alcohol recidivism after transplant. The health maintenance studies discussed behaviors such as smoking, clinic appointment attendance, or vaccination/health screening behaviors of recipients.

DISCUSSION

Self-management studies in liver recipients have been narrowly focused on medication nonadherence and alcohol recidivism. To improve self-management in recipients, self-management beyond medication nonadherence and alcohol recidivism should be comprehensively examined.

摘要

引言

尽管自我管理对肝移植受者至关重要,但尚无综述对该人群中与自我管理相关的研究结果进行综合分析。

目的

本叙述性综述旨在综合当前研究结果,并找出肝移植受者自我管理方面的知识空白。

方法

使用以下检索词在PubMed、CINAHL Plus、PsychINFO、ProQuest和Web of Science数据库中进行检索:[自我护理或自我管理或健康行为] 以及 [肝移植]。选取关注成年受者自我管理的同行评议发表研究文章。共纳入23篇文章进行综述。两名评审员独立审阅所选文章的全文,并提取有关自我管理的定义、测量方法和研究结果的数据。

结果

确定了自我管理的三个领域,包括用药依从性差(n = 11)、酒精复饮(n = 11)和健康维持(n = 5)。报告的用药依从性差发生率在8%至66%之间。用药依从性差与受者的人口统计学特征(如年龄或性别)、移植相关因素(如移植后的时间)以及移植前变量(如药物/酒精滥用史)有关。报告的酒精复饮率在3%至95%之间。年龄、移植前变量(如移植前戒酒时间)和人格障碍被确定与移植后酒精复饮有关。健康维持研究讨论了受者的吸烟、门诊预约就诊或疫苗接种/健康筛查行为等。

讨论

肝移植受者的自我管理研究主要集中在用药依从性差和酒精复饮方面。为了改善受者的自我管理,应全面研究用药依从性差和酒精复饮之外的自我管理。

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