Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul, 151-921, Republic of Korea.
Phyzen Genome Institute, Seongnam-si, Gyeonggi-do, 13558, Republic of Korea.
BMC Plant Biol. 2018 Apr 12;18(1):62. doi: 10.1186/s12870-018-1282-9.
The ginseng (Panax ginseng C.A. Meyer) is a perennial herbaceous plant that has been used in traditional oriental medicine for thousands of years. Ginsenosides, which have significant pharmacological effects on human health, are the foremost bioactive constituents in this plant. Having realized the importance of this plant to humans, an integrated omics resource becomes indispensable to facilitate genomic research, molecular breeding and pharmacological study of this herb.
The first draft genome sequences of P. ginseng cultivar "Chunpoong" were reported recently. Here, using the draft genome, transcriptome, and functional annotation datasets of P. ginseng, we have constructed the Ginseng Genome Database http://ginsengdb.snu.ac.kr /, the first open-access platform to provide comprehensive genomic resources of P. ginseng. The current version of this database provides the most up-to-date draft genome sequence (of approximately 3000 Mbp of scaffold sequences) along with the structural and functional annotations for 59,352 genes and digital expression of genes based on transcriptome data from different tissues, growth stages and treatments. In addition, tools for visualization and the genomic data from various analyses are provided. All data in the database were manually curated and integrated within a user-friendly query page.
This database provides valuable resources for a range of research fields related to P. ginseng and other species belonging to the Apiales order as well as for plant research communities in general. Ginseng genome database can be accessed at http://ginsengdb.snu.ac.kr /.
人参(Panax ginseng C.A. Meyer)是一种多年生草本植物,在传统的东方医学中已经使用了数千年。人参皂苷是这种植物中最重要的生物活性成分,对人类健康具有重要的药理作用。鉴于这种植物对人类的重要性,一个综合的组学资源对于促进该植物的基因组研究、分子育种和药理学研究变得不可或缺。
最近报道了人参栽培品种“春蓬”的第一个基因组草图序列。在这里,我们使用人参的基因组草图、转录组和功能注释数据集,构建了人参基因组数据库 http://ginsengdb.snu.ac.kr /,这是第一个提供人参综合基因组资源的开放访问平台。该数据库的当前版本提供了最新的基因组草图序列(约 3000 Mbp 的支架序列),以及 59352 个基因的结构和功能注释,以及基于不同组织、生长阶段和处理的转录组数据的基因数字表达。此外,还提供了可视化工具和各种分析的基因组数据。数据库中的所有数据均经过人工整理,并整合在一个用户友好的查询页面中。
该数据库为与人参相关的一系列研究领域以及一般的植物研究社区提供了有价值的资源。人参基因组数据库可在 http://ginsengdb.snu.ac.kr / 访问。