National Institute of Technology, Karnataka, India.
Indian Institute of Technology, Kharagpur, India.
Comput Methods Programs Biomed. 2018 Jun;159:199-209. doi: 10.1016/j.cmpb.2018.03.016. Epub 2018 Mar 22.
The stethoscope based auscultation technique is a primary diagnostic tool for chest sound analysis. However, the performance of this method is limited due to its dependency on physicians experience, knowledge and also clarity of the signal. To overcome this problem we need an automated computer-aided diagnostic system that will be competent in noisy environment. In this paper, a novel feature extraction technique is introduced for discriminating various pulmonary dysfunctions in an automated way based on pattern recognition algorithms.
In this work, the disease correlated relevant characteristics of lung sounds signals are identified in terms of statistical distribution parameters: mean, variance, skewness, and kurtosis. These features are extracted from selective morphological components of the mapped signal in the empirical mode decomposition domain. The feature set is fed to the classifier model to differentiate their corresponding classes.
The significance of features developed are validated by conducting several experiments using supervised and unsupervised classifiers. Furthermore, the discriminating power of the proposed features is compared with three types of baseline features. The experimental result is evaluated by statistical analysis and also validated with physicians inference.
It is found that the proposed features extraction technique is superior to the baseline methods in terms of classification accuracy, sensitivity and specificity. The developed method gives better results compared to baseline methods in any circumstance. The proposed method gives a higher accuracy of 94.16, sensitivity of 100 and specificity of 93.75 for an artificial neural network classifier.
听诊器听诊技术是胸部声音分析的主要诊断工具。然而,由于其对医生经验、知识以及信号清晰度的依赖性,该方法的性能受到限制。为了克服这个问题,我们需要一种能够胜任嘈杂环境的自动化计算机辅助诊断系统。在本文中,我们提出了一种新的特征提取技术,该技术基于模式识别算法,可自动区分各种肺部功能障碍。
在这项工作中,从经验模态分解域中映射信号的选择性形态成分中提取与疾病相关的相关特征,以统计分布参数(均值、方差、偏度和峰度)表示。将特征集输入分类器模型以区分它们的对应类别。
通过使用监督和无监督分类器进行多项实验验证了所开发特征的重要性。此外,还比较了所提出特征与三种基线特征的判别能力。通过统计分析和医生推断对实验结果进行了评估。
发现与基线方法相比,所提出的特征提取技术在分类准确性、敏感性和特异性方面具有优势。在任何情况下,所开发的方法都比基线方法的结果更好。对于人工神经网络分类器,该方法的准确率为 94.16%,灵敏度为 100%,特异性为 93.75%。