纺锤体微管的不对称酪氨酸化促进了自私遗传。
Asymmetric Tyrosination of Spindle Microtubules Facilitates Selfish Inheritance.
机构信息
Department of Biochemistry, Indian Institute of Science, C. V. Raman Avenue, Bangalore, Karnataka, 560012, India.
出版信息
Trends Cell Biol. 2018 Jun;28(6):417-419. doi: 10.1016/j.tcb.2018.03.005. Epub 2018 Apr 10.
PMID:29650359
Abstract
Meiotic drive is an enigmatic process that results from biased segregation of selfish genetic elements that enhance their own transmission and drive evolution. During asymmetric female meiotic divisions, selfish elements segregate preferentially towards the egg rather than polar bodies. Recent findings demonstrate that asymmetric spindle tyrosination helps selfish elements to cheat.
摘要
减数分裂驱动是一种神秘的过程，源于自私遗传元件的偏置分离，这些元件增强了自身的传递并推动了进化。在不对称的雌性减数分裂中，自私元件优先向卵子而不是极体分离。最近的发现表明，不对称纺锤体酪氨酸化有助于自私元件作弊。
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