Soulsby E J
University of Cambridge, Department of Clinical Veterinary Medicine, U.K.
Immunol Lett. 1987 Dec;16(3-4):315-20. doi: 10.1016/0165-2478(87)90164-7.
A selective review is given of the mechanisms associated with the evasion of the immune response by parasitic helminths and immunological unresponsiveness as it applies to helminth infections. Immunosuppression caused by parasites leading to reduced responsiveness of lymphocytes to mitogens is discussed, and mechanisms that inhibit effector mechanisms at the parasite surface and polyclonal activation of lymphocyte populations are dealt with. Physiological immunosuppression associated with parturition and lactation and the immunological unresponsiveness of young ruminants are dealt with in detail.
本文对寄生蠕虫逃避免疫反应的相关机制以及适用于蠕虫感染的免疫无反应性进行了选择性综述。讨论了寄生虫引起的免疫抑制导致淋巴细胞对丝裂原反应性降低的情况，并探讨了抑制寄生虫表面效应机制和淋巴细胞群体多克隆激活的机制。详细阐述了与分娩和哺乳相关的生理免疫抑制以及幼龄反刍动物的免疫无反应性。
