Qualizza Rosanna, Losappio Laura M, Furci Fabiana
1Allergy Service, ASST Nord Milano, Milan, Italy.
2Allergy Department, Niguarda Ca' Granda Hospital, Milan, Italy.
Clin Mol Allergy. 2018 Apr 10;16:10. doi: 10.1186/s12948-018-0088-5. eCollection 2018.
Parasite infections stimulate total and specific IgE production that, in the case of infection, corresponds to chronic allergic symptoms. There may also be other infections which have similar symptoms, such as infection. is a large nematode that causes abdominal pain, nausea, vomiting, bloating, anorexia and intermittent diarrhoea. Patients with ascaridiasis and high IgE levels may also have allergy-like symptoms such as asthma, urticaria and atopic dermatitis.
We report a case of atopic dermatitis caused by Ascaris lumbricoides which shows the important role of parasitic infection in patients with long-lasting dermatitis. The patient was a 12-year old female suffering since early infancy from atopic dermatitis and asthma. She was treated for dermatitis with oral bethametasone and topical pimecrolimus with little benefit. After two cycles of mebendazole therapy, the patient showed progressive improvement of symptoms.
In patients with dermatitis, Ascaris lumbricoides infection should be not excluded: adequate anthelmintic treatment may result in complete regression from the disease.
寄生虫感染会刺激总IgE和特异性IgE的产生，在感染的情况下，这与慢性过敏症状相对应。也可能存在其他具有类似症状的感染，如感染。蛔虫是一种大型线虫，可引起腹痛、恶心、呕吐、腹胀、厌食和间歇性腹泻。蛔虫病患者且IgE水平较高时，也可能出现类似过敏的症状，如哮喘、荨麻疹和特应性皮炎。
我们报告一例由蛔虫引起的特应性皮炎病例，该病例显示了寄生虫感染在长期性皮炎患者中的重要作用。患者为一名12岁女性，自幼患有特应性皮炎和哮喘。她接受了口服倍他米松和外用吡美莫司治疗皮炎，但效果甚微。经过两个周期的甲苯达唑治疗后，患者症状逐渐改善。
对于皮炎患者，不应排除蛔虫感染：适当的驱虫治疗可能使疾病完全消退。
