Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota and Department of Nutrition and Exercise Physiology, University of Missouri , Columbia, Missouri.
Physiol Genomics. 2018 Jul 1;50(7):504-509. doi: 10.1152/physiolgenomics.00032.2018. Epub 2018 Apr 13.
Known primarily for its oxygen-sensing capabilities, the carotid body chemoreceptors have recently been implicated, primarily by work in animal models, in the pathophysiology of a number of metabolic conditions. The research presented in this brief review highlights translational work conducted at the Mayo Clinic between 2010 and 2017 in healthy humans and discusses key areas for future work in disease populations.
颈动脉体化学感受器主要因其氧感应能力而闻名,最近主要通过动物模型的研究,在多种代谢疾病的病理生理学中发挥作用。本篇简要综述介绍了梅奥诊所 2010 年至 2017 年期间在健康人群中进行的转化研究,并讨论了疾病人群中未来工作的重点领域。