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Interindividual variability in the dose-specific effect of dopamine on carotid chemoreceptor sensitivity to hypoxia.多巴胺对颈动脉化学感受器低氧敏感性的剂量特异性效应存在个体间差异。
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Hyperbaric Oxygen Therapy Improves Glucose Homeostasis in Type 2 Diabetes Patients: A Likely Involvement of the Carotid Bodies.高压氧疗法改善2型糖尿病患者的血糖稳态:颈动脉体可能参与其中。
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Exercise training attenuates chemoreflex-mediated reductions of renal blood flow in heart failure.运动训练可减轻心力衰竭中化学反射介导的肾血流量减少。
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Effect of bilateral carotid body resection on cardiac baroreflex control of blood pressure during hypoglycemia.双侧颈动脉体切除对低血糖期间血压的心脏压力反射控制的影响。
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人体中的葡萄糖、胰岛素和颈动脉体化学感受器。

Glucose, insulin, and the carotid body chemoreceptors in humans.

机构信息

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota and Department of Nutrition and Exercise Physiology, University of Missouri , Columbia, Missouri.

出版信息

Physiol Genomics. 2018 Jul 1;50(7):504-509. doi: 10.1152/physiolgenomics.00032.2018. Epub 2018 Apr 13.

DOI:10.1152/physiolgenomics.00032.2018
PMID:29652633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6087880/
Abstract

Known primarily for its oxygen-sensing capabilities, the carotid body chemoreceptors have recently been implicated, primarily by work in animal models, in the pathophysiology of a number of metabolic conditions. The research presented in this brief review highlights translational work conducted at the Mayo Clinic between 2010 and 2017 in healthy humans and discusses key areas for future work in disease populations.

摘要

颈动脉体化学感受器主要因其氧感应能力而闻名,最近主要通过动物模型的研究,在多种代谢疾病的病理生理学中发挥作用。本篇简要综述介绍了梅奥诊所 2010 年至 2017 年期间在健康人群中进行的转化研究,并讨论了疾病人群中未来工作的重点领域。