• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

衰老过程中的微血管和骨骼肌健康。

The Microvasculature and Skeletal Muscle Health in Aging.

机构信息

Baltimore Veterans Affairs Geriatric Research, Education and Clinical Center.

Department of Medicine, University of Maryland School of Medicine, Baltimore.

出版信息

Exerc Sport Sci Rev. 2018 Jul;46(3):172-179. doi: 10.1249/JES.0000000000000151.

DOI:10.1249/JES.0000000000000151
PMID:29652695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6005745/
Abstract

Aging and aging-related declines in physical activity are associated with physical and metabolic impairments. Skeletal muscle capillarization is reduced in sedentary older adults, may contribute to impairments in skeletal muscle, and is modifiable by exercise training. This article examines the hypothesis that preservation of skeletal muscle capillarization is essential to maintain metabolism, fitness, and function with aging.

摘要

随着年龄的增长和与年龄相关的体力活动减少，身体和代谢功能都会受到影响。久坐的老年人骨骼肌的毛细血管化减少，可能导致骨骼肌功能受损，而运动训练可以改变这种情况。本文探讨了一个假设，即保持骨骼肌的毛细血管化对于维持新陈代谢、健康和功能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/0a98fb7327e9/nihms958886f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/3c6abf77b121/nihms958886f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/7c17a8c19f65/nihms958886f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/0a98fb7327e9/nihms958886f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/3c6abf77b121/nihms958886f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/7c17a8c19f65/nihms958886f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f8/6005745/0a98fb7327e9/nihms958886f3.jpg

相似文献

1
The Microvasculature and Skeletal Muscle Health in Aging.衰老过程中的微血管和骨骼肌健康。
Exerc Sport Sci Rev. 2018 Jul;46(3):172-179. doi: 10.1249/JES.0000000000000151.
2
Comment on Prior et al. Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining. Diabetes 2015;64:3386-3395.对普赖尔等人的评论。运动训练和停训后，骨骼肌毛细血管化增加可独立增强老年人的胰岛素敏感性。《糖尿病》2015年；64卷：3386 - 3395页
Diabetes. 2016 Mar;65(3):e11-2. doi: 10.2337/db15-1461.
3
Response to Comment on Prior et al. Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining. Diabetes 2015;64:3386-3395.对关于普赖尔等人的评论的回应。运动训练和停训后，骨骼肌毛细血管增多独立增强老年人胰岛素敏感性。《糖尿病》2015年；64卷：3386 - 3395页
Diabetes. 2016 Mar;65(3):e13-4. doi: 10.2337/dbi15-0038.
4
Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults.肌肉减少症与老年人较低的骨骼肌毛细血管化及运动能力相关。
J Gerontol A Biol Sci Med Sci. 2016 Aug;71(8):1096-101. doi: 10.1093/gerona/glw017. Epub 2016 Feb 17.
5
Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining.运动训练和停训后，骨骼肌毛细血管化增加可独立增强老年人的胰岛素敏感性。
Diabetes. 2015 Oct;64(10):3386-95. doi: 10.2337/db14-1771. Epub 2015 Jun 11.
6
Lower capillarization, VEGF protein, and VEGF mRNA response to acute exercise in the vastus lateralis muscle of aged vs. young women.老年女性与年轻女性股外侧肌中毛细血管化程度、VEGF蛋白以及VEGF mRNA对急性运动的反应较低。
J Appl Physiol (1985). 2005 Nov;99(5):1872-9. doi: 10.1152/japplphysiol.00498.2005. Epub 2005 Jul 14.
7
The effect of different training modes on skeletal muscle microvascular density and endothelial enzymes controlling NO availability.不同训练模式对骨骼肌微血管密度及控制一氧化氮可用性的内皮酶的影响。
J Physiol. 2016 Apr 15;594(8):2245-57. doi: 10.1113/JP270329. Epub 2015 Apr 16.
8
The influence of endurance and resistance exercise on muscle capillarization in the elderly: a review.耐力和阻力运动对老年人肌肉毛细血管化的影响：综述
Acta Physiol Scand. 2005 Oct;185(2):89-97. doi: 10.1111/j.1365-201X.2005.01461.x.
9
Resistance Training Increases Skeletal Muscle Capillarization in Healthy Older Men.阻力训练可增加健康老年男性的骨骼肌毛细血管密度。
Med Sci Sports Exerc. 2016 Nov;48(11):2157-2164. doi: 10.1249/MSS.0000000000001019.
10
[Physical activity and aging].[体育活动与衰老]
Schweiz Med Wochenschr. 1998 Aug 4;128(31-32):1181-6.

引用本文的文献

1
Feasibility of unsupervised, home-based leg heat therapy in older adults: a pilot, sham-controlled trial.老年人居家无监督腿部热疗的可行性：一项试点、假对照试验
J Appl Physiol (1985). 2025 Sep 1;139(3):668-684. doi: 10.1152/japplphysiol.00285.2025. Epub 2025 Aug 1.
2
Pathophysiology of Myopenia in rheumatoid arthritis.类风湿关节炎中肌肉减少症的病理生理学
Bone Res. 2025 Jun 16;13(1):64. doi: 10.1038/s41413-025-00438-9.
3
Rest-to-work and work-to-rest transients of interstitial PO in spinotrapezius muscle of young and old male rats.年轻和老年雄性大鼠斜方肌间质氧分压的从休息到工作以及从工作到休息的瞬态变化。
Physiol Rep. 2025 Mar;13(5):e70260. doi: 10.14814/phy2.70260.
4
Association between Pan-Immune Inflammation Value and Sarcopenia in Hypertensive Patients, NHANES 1999-2018.1999 - 2018年美国国家健康与营养检查调查中高血压患者的全免疫炎症值与肌肉减少症之间的关联
J Clin Hypertens (Greenwich). 2025 Jan;27(1):e14944. doi: 10.1111/jch.14944. Epub 2024 Nov 17.
5
The effects of myosteatosis on skeletal muscle function in older adults.肌肉脂肪化对老年人骨骼肌功能的影响。
Physiol Rep. 2024 May;12(9):e16042. doi: 10.14814/phy2.16042.
6
A high-resolution view of the heterogeneous aging endothelium.高分辨率观察异质性衰老的血管内皮细胞。
Angiogenesis. 2024 May;27(2):129-145. doi: 10.1007/s10456-023-09904-6. Epub 2024 Feb 7.
7
An examination of the validity of neuropsychological and physical testing batteries in Latin-American adults aged over 55 years.对 55 岁以上拉丁美洲成年人的神经心理学和身体测试组合的有效性进行研究。
Aging Clin Exp Res. 2023 Dec;35(12):3157-3165. doi: 10.1007/s40520-023-02612-7. Epub 2023 Nov 21.
8
Vascular dysfunction and the age-related decline in critical power.血管功能障碍与关键力量随年龄的下降。
Exp Physiol. 2024 Feb;109(2):240-254. doi: 10.1113/EP091571. Epub 2023 Nov 7.
9
Association of estimated carotid-femoral pulse wave velocity with frailty in middle-aged and older adults with cardiometabolic disease.估算的颈-股脉搏波速度与中年和老年合并心血管代谢疾病患者虚弱的关系。
Aging Clin Exp Res. 2023 Nov;35(11):2425-2436. doi: 10.1007/s40520-023-02556-y. Epub 2023 Sep 12.
10
Diabetes diminishes muscle precursor cell-mediated microvascular angiogenesis.糖尿病会减弱肌前体细胞介导的微血管生成。
PLoS One. 2023 Aug 4;18(8):e0289477. doi: 10.1371/journal.pone.0289477. eCollection 2023.

本文引用的文献

1
Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans.肌纤维毛细血管化作为人类胰岛素敏感性指标的决定因素。
Physiol Rep. 2017 May;5(10):e13278. doi: 10.14814/phy2.13278.
2
Coupling between skeletal muscle fiber size and capillarization is maintained during healthy aging.在健康衰老过程中，骨骼肌纤维大小与毛细血管化之间的耦合得以维持。
J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):647-659. doi: 10.1002/jcsm.12194. Epub 2017 Apr 5.
3
Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men.在老年男性的抗阻训练中，肌纤维毛细血管化是肌纤维肥大的关键因素。
J Cachexia Sarcopenia Muscle. 2017 Apr;8(2):267-276. doi: 10.1002/jcsm.12137. Epub 2016 Aug 4.
4
Resistance Training Increases Skeletal Muscle Capillarization in Healthy Older Men.阻力训练可增加健康老年男性的骨骼肌毛细血管密度。
Med Sci Sports Exerc. 2016 Nov;48(11):2157-2164. doi: 10.1249/MSS.0000000000001019.
5
Skeletal muscle satellite cells are located at a closer proximity to capillaries in healthy young compared with older men.与老年人相比，健康的年轻人的骨骼肌卫星细胞更接近毛细血管。
J Cachexia Sarcopenia Muscle. 2016 Dec;7(5):547-554. doi: 10.1002/jcsm.12105. Epub 2016 Feb 15.
6
Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults.肌肉减少症与老年人较低的骨骼肌毛细血管化及运动能力相关。
J Gerontol A Biol Sci Med Sci. 2016 Aug;71(8):1096-101. doi: 10.1093/gerona/glw017. Epub 2016 Feb 17.
7
Skeletal muscle morphology in sarcopenia defined using the EWGSOP criteria: findings from the Hertfordshire Sarcopenia Study (HSS).使用 EWGSOP 标准定义的肌少症中的骨骼肌形态：赫特福德郡肌少症研究（HSS）的结果。
BMC Geriatr. 2015 Dec 18;15:171. doi: 10.1186/s12877-015-0171-4.
8
Skeletal myofiber VEGF is necessary for myogenic and contractile adaptations to functional overload of the plantaris in adult mice.成年小鼠中，骨骼肌纤维血管内皮生长因子（VEGF）对于比目鱼肌功能超负荷时的肌源性和收缩适应性是必需的。
J Appl Physiol (1985). 2016 Jan 15;120(2):188-95. doi: 10.1152/japplphysiol.00638.2015. Epub 2015 Nov 5.
9
Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012.美国成年人糖尿病患病率及趋势（1988 年至 2012 年）。
JAMA. 2015 Sep 8;314(10):1021-9. doi: 10.1001/jama.2015.10029.
10
Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining.运动训练和停训后，骨骼肌毛细血管化增加可独立增强老年人的胰岛素敏感性。
Diabetes. 2015 Oct;64(10):3386-95. doi: 10.2337/db14-1771. Epub 2015 Jun 11.