Torner Núria, Martínez Ana, Basile Luca, Mosquera MMar, Antón Andrés, Rius Cristina, Sala M Rosa, Minguell Sofia, Plasencia Elsa, Carol Mónica, Godoy Pere, Follia Núria, Barrabeig Irene, Marcos M Angeles, Pumarola Tomàs, Jané Mireia
Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.
CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.
BMC Res Notes. 2018 Apr 14;11(1):244. doi: 10.1186/s13104-018-3349-y.
The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons.
From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010-2011 to 2014-2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0-101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment.
加泰罗尼亚急性呼吸道感染信息计划（PIDIRAC）在2009年纳入了对实验室确诊流感的严重住院病例（SHCLCI）的监测。本研究的目的是确定在五个流感季节期间，12家哨点医院记录的SHCLCI的临床、流行病学和病毒学特征。
从2010 - 2011年至2014 - 2015年的5个流感流行季节记录的SHCLCI样本中，病例通过呼吸道样本的细胞培养中的PCR和/或病毒分离得以确诊。共记录了1400例SHCLCI，33%的病例需要入住重症监护病房（ICU），12%的病例死亡。病例的中位年龄为61岁（范围0 - 101岁）；70.5%未接种疫苗；80.4%接受了抗病毒治疗（分别在入院后48小时内和症状出现后，79.6%和24%的病例接受了治疗）；87.7%的病例中鉴定出甲型流感病毒[37.9%为甲型（H1N1）pdm09，29.3%为甲型（H3N2）]。对SHCLCI的监测可估计季节性流感流行的严重程度，并识别和描述高危人群，以便促进预防措施，如接种疫苗和早期抗病毒治疗。
