Bolanca-Bumber S, Basta-Juzbasić A, Kansky A, Gross T
Department of Dermatology, Clinical Center Zagreb, Yugoslavia.
Arch Dermatol Res. 1988;280(1):54-6. doi: 10.1007/BF00412690.
In severe cases of acne conglobata the use of substances which considerably reduce the sebum excretion rate, such as 13-cis-retinoic acid, is reasonable. To monitor the effect of such preparation a noninvasive and accurate method for measuring skin surface lipids (SSLs) is required. A new modified photometric quantification of SSLs sampled using the cigarette paper method based on reaction with phosphovanilic reagent was introduced. Our overall results indicate that a 3-h SSLs assessment measured photometrically is as accurate as the gravimetric technique; it is reproducible in situations with low and high levels of SSLs.
在聚合性痤疮的严重病例中，使用能显著降低皮脂排泄率的物质，如13 - 顺式维甲酸，是合理的。为监测此类制剂的效果，需要一种无创且准确的测量皮肤表面脂质（SSLs）的方法。引入了一种基于与磷香草醛试剂反应的卷烟纸法对SSLs进行采样的新型改良光度法定量方法。我们的总体结果表明，通过光度法进行的3小时SSLs评估与重量法一样准确；在SSLs水平低和高的情况下均可重复。
