Council for Nutritional and Environmental Medicine, Toften 24, 8610, Mo i Rana, Norway.
Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Biol Trace Elem Res. 2018 Dec;186(2):384-394. doi: 10.1007/s12011-018-1336-8. Epub 2018 Apr 14.
Daily ingestion of lead (Pb), even through piped drinking water, has long time been an important issue of concern, attracting for decades research in environmental science and toxicology, and again comes to prominence because of recent high-profile cases of exposure of populations in several countries to Pb-contaminated water. Numerous studies have reported an association between Pb in water and the risk of cardiovascular pathologies. Low levels of magnesium and calcium, i.e., low degree of hardness of the drinking water, may accentuate Pb leaching from water pipes and furthermore increase Pb absorption. This review evaluates the evidence for an association between Pb exposure from drinking water and cardiovascular end points in human populations.
人们长期以来一直关注日常生活中铅（Pb）的摄入，即使是通过管道饮用水，这是一个重要的问题，几十年来一直是环境科学和毒理学研究的重点，而最近一些国家的人群因暴露于受 Pb 污染的水中而成为焦点，再次引起了人们的关注。许多研究报告称，水中的 Pb 与心血管病理风险之间存在关联。镁和钙的低水平，即饮用水的低硬度程度，可能会加剧水管中 Pb 的浸出，并进一步增加 Pb 的吸收。这篇综述评估了人类饮用水中 Pb 暴露与心血管终点之间关联的证据。
