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对一组100例患者进行12个月随访,分析其在ACDF手术后颈椎曲度和椎间盘间隙高度的变化。

Analysis of changes in cervical spinal curvature and intervertebral disk space height following ACDF surgery in a group of 100 patients followed up for 12 months.

作者信息

Godlewski Bartosz, Stachura Magdalena Katarzyna, Czepko Ryszard Adam, Banach Mariusz, Czepko Ryszard

机构信息

Department of Neurosurgery, Scanmed - St. Raphael Hospital, 12 Bochenka Street, 30-693 Cracow, Poland.

Department of Neurosurgery, Scanmed - St. Raphael Hospital, 12 Bochenka Street, 30-693 Cracow, Poland.

出版信息

J Clin Neurosci. 2018 Jun;52:92-99. doi: 10.1016/j.jocn.2018.04.005. Epub 2018 Apr 12.

Abstract

We analysed 100 patients following anterior cervical discectomy and fusion with interbody stabilisation with PEEK cages. Radiographs obtained preoperatively and during the 12-month follow-up were compared to track changes in overall and local cervical lordosis and disk space height. Subsidence was defined as cage migration ≥ 3 mm into the adjacent endplates. Mean change in operated disk space height was 1.13 ± 1.33 mm. Subsidence was detected in 10.23% of the operated spaces. Mean change in overall cervical lordosis was 1.31 ± 5.71 degrees, and mean change in local lordosis was 0.19 ± 4.71 degrees. Change in overall cervical lordosis correlated with change in local lordosis (r = 0.61, p < 0.01). The greatest changes in lordosis and disk space height were noted immediately post-surgery. Baseline values were approximated gradually over time, but the post-operative values at 12 months were still higher than baseline. Disk space height change did not correlate with changes in patient-reported pain intensity at baseline (VAS 0) vs. at 12 months post-operatively (VAS 12) (r = 0.12, p < 0.05) or changes in the Neck Disability Index (NDI) at baseline (NDI 0) vs. at 12 months post-operatively (NDI 12) (r = -0.02, p = 0.05). Changes in overall cervical lordosis did not directly influence treatment outcomes assessed by comparing VAS 0 vs. VAS 12 (r = 0.13, p = 0.24) or NDI 0 vs. NDI 12 (r = -0.0005, p = 0.96). Surgical outcomes depend primarily on adequate decompression of the spinal cord and nerve roots. Post-operative radiological changes did not directly influence patients' pain level or quality of life.

摘要

我们分析了100例行前路颈椎间盘切除术并采用聚醚醚酮椎间融合器进行椎间稳定融合术的患者。比较术前及术后12个月获得的X线片,以追踪颈椎整体及局部生理前凸和椎间隙高度的变化。下沉定义为椎间融合器向相邻终板迁移≥3mm。手术节段椎间隙高度的平均变化为1.13±1.33mm。在10.23%的手术节段检测到下沉。颈椎整体生理前凸的平均变化为1.31±5.71度,局部生理前凸的平均变化为0.19±4.71度。颈椎整体生理前凸的变化与局部生理前凸的变化相关(r=0.61,p<0.01)。生理前凸和椎间隙高度的最大变化在术后即刻出现。随着时间的推移,基线值逐渐接近,但术后12个月的值仍高于基线。椎间隙高度变化与患者术前(视觉模拟评分0分)及术后12个月(视觉模拟评分12分)报告的疼痛强度变化无关(r=0.12,p<0.05),也与术前(颈部功能障碍指数0分)及术后12个月(颈部功能障碍指数12分)的颈部功能障碍指数变化无关(r=-0.02,p=0.05)。通过比较视觉模拟评分0分与12分(r=0.13,p=0.24)或颈部功能障碍指数0分与12分(r=-0.0005,p=0.96)评估,颈椎整体生理前凸的变化并未直接影响治疗效果。手术效果主要取决于脊髓和神经根的充分减压。术后影像学变化并未直接影响患者的疼痛程度或生活质量。

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