Lee Jina, Kim Yun-Mi, Park Young-Kyu, Yang Young-Cheol, Jung Bock-Gie, Lee Bong-Joo
Department of Veterinary Infectious Diseases, College of Veterinary Medicine, Chonnam National University, Gwangju 500-757, Republic of Korea.
Current address: Center for Virology and Vaccine Research, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02115, U.S.A.
J Vet Med Sci. 2018 May 18;80(5):736-740. doi: 10.1292/jvms.17-0236. Epub 2018 Apr 16.
Black soldier fly (Hermetia illucens) larvae (BSFL) are rich in protein and have the potential to be used in animal feed. The aim of the present study was to determine the immunoprophylactic effect of BSFL against Salmonella Gallinarum in broiler chicks as an alternative feed additive. Results showed that BSFL improved body weight gain and increased frequency of CD4+ T lymphocyte, serum lysozyme activity, and spleen lymphocyte proliferation. Moreover, BSFL reinforced bacterial clearance and increased survivability of broiler chicks against S. Gallinarum. These data suggested that BSFL has prophylactic properties with stimulating non-specific immune responses, as well as reduced bacterial burden against S. Gallinarum.
黑水虻（亮斑扁角水虻）幼虫富含蛋白质，有潜力用于动物饲料。本研究的目的是确定黑水虻幼虫作为一种替代饲料添加剂对肉鸡感染鸡沙门氏菌的免疫预防作用。结果表明，黑水虻幼虫提高了肉鸡的体重增加，并增加了CD4+ T淋巴细胞的频率、血清溶菌酶活性和脾脏淋巴细胞增殖。此外，黑水虻幼虫增强了细菌清除能力，并提高了肉鸡抵抗鸡沙门氏菌的存活率。这些数据表明，黑水虻幼虫具有预防特性，可刺激非特异性免疫反应，并减少鸡沙门氏菌的细菌负荷。
