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并非所有作为非阵发性心房颤动有效消融靶点的转子都包含在心房颤动驱动因素的传统间接指标所提示的区域内:ExTRa Mapping项目。

Not all rotors, effective ablation targets for nonparoxysmal atrial fibrillation, are included in areas suggested by conventional indirect indicators of atrial fibrillation drivers: ExTRa Mapping project.

作者信息

Sakata Kensuke, Okuyama Yusuke, Ozawa Tomoya, Haraguchi Ryo, Nakazawa Kazuo, Tsuchiya Takeshi, Horie Minoru, Ashihara Takashi

机构信息

Department of Cardiovascular Medicine Shiga University of Medical Science Otsu Japan.

Graduate School of Applied Informatics University of Hyogo Kobe Japan.

出版信息

J Arrhythm. 2018 Mar 8;34(2):176-184. doi: 10.1002/joa3.12036. eCollection 2018 Apr.

DOI:10.1002/joa3.12036
PMID:29657593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5891413/
Abstract

BACKGROUND

Effects of nonparoxysmal atrial fibrillation (non-PAF) ablation targeting complex fractionated atrial electrogram (CFAE) areas and/or low voltage areas (LVAs) are still controversial.

METHODS AND RESULTS

A recently developed online real-time phase mapping system (ExTRa Mapping) was used to conduct LVA mapping and simultaneous ExTRa and CFAE mapping in 28 non-PAF patients after pulmonary vein isolation (PVI). Nonpassively activated areas, in the form of meandering rotors and/or multiple wavelets assumed to contain non-PAF drivers, partly overlapped with CFAE/LVAs but not always coincided with them.

CONCLUSION

Real-time rotor imaging, rather than conventional indirect indicators only, might be very useful for detecting non-PAF drivers.

摘要

背景

针对复杂碎裂心房电图(CFAE)区域和/或低电压区域(LVA)进行非阵发性心房颤动(non-PAF)消融的效果仍存在争议。

方法与结果

使用一种最近开发的在线实时相位标测系统(ExTRa Mapping),对28例肺静脉隔离(PVI)后的非PAF患者进行LVA标测以及同步的ExTRa和CFAE标测。以蜿蜒转子和/或多个小波形式存在的非被动激活区域,被认为包含非PAF驱动因素,部分与CFAE/LVA重叠,但并非总是与之重合。

结论

实时转子成像,而非仅传统的间接指标,可能对检测非PAF驱动因素非常有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/a9a21f8336e3/JOA3-34-176-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/4d69b72c0cc7/JOA3-34-176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/9a3d22fbe1bd/JOA3-34-176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/1a32a02c642d/JOA3-34-176-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/2f7ddab20014/JOA3-34-176-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/2214a56fc86e/JOA3-34-176-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/c91321f4492d/JOA3-34-176-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/a9a21f8336e3/JOA3-34-176-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/4d69b72c0cc7/JOA3-34-176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/9a3d22fbe1bd/JOA3-34-176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/1a32a02c642d/JOA3-34-176-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/2f7ddab20014/JOA3-34-176-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/2214a56fc86e/JOA3-34-176-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/c91321f4492d/JOA3-34-176-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742c/5891413/a9a21f8336e3/JOA3-34-176-g007.jpg

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Assessing the arrhythmogenic propensity of fibrotic substrate using digital twins to inform a mechanisms-based atrial fibrillation ablation strategy.使用数字孪生评估纤维化基质的致心律失常倾向,以制定基于机制的心房颤动消融策略。
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