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三例同步原发性恶性肿瘤的成功治疗——关于外科、病理和肿瘤学方面及决策的思考

Successful treatment of three synchronous primary malignant tumours-reflection on surgical, pathological and oncological aspects and decision making.

作者信息

Ágoston Emese Irma, Somorácz Áron, Madaras Lilla, Zaránd Attila, Szentmártoni Gyöngyvér, Orosz Zsuzsanna, Dank Magdolna, Baranyai Zsolt

机构信息

1st Department of Surgery, Semmelweis University, 78 Üllői út, 1082 Budapest, Hungary.

2nd Institution of Pathology, Semmelweis University, 93 Üllői út, Budapest 1091, Hungary.

出版信息

J Surg Case Rep. 2018 Apr 6;2018(4):rjy041. doi: 10.1093/jscr/rjy041. eCollection 2018 Apr.

Abstract

We report a case of a patient with triple synchronous primary malignancies (breast, colon, kidney) which has not been previously reported in the literature. A 70-year-old woman was diagnosed with invasive ductal carcinoma of the left breast with axillary lymph node metastasis. During the staging period, renal cell carcinoma on the left kidney and mucinous adenocarcinoma in the proximal colon were found. Since the breast tumour demonstrated favourable biology, aromatase inhibitor therapy had been started and simultaneous right colectomy and left nephrectomy was performed. Six months after the first diagnosis, left sector excision and axillary block dissection were performed. Adjuvant FEC chemotherapy was administered, followed by radiotherapy. During the 16-month follow-up period disease recurrence was not detected.

摘要

我们报告一例患有三重同步原发性恶性肿瘤(乳腺癌、结肠癌、肾癌)的患者,此前文献中未见报道。一名70岁女性被诊断为左乳腺浸润性导管癌伴腋窝淋巴结转移。在分期检查期间,发现左肾有肾细胞癌,近端结肠有黏液腺癌。由于乳腺肿瘤显示出良好的生物学特性,已开始使用芳香化酶抑制剂治疗,并同时进行了右半结肠切除术和左肾切除术。首次诊断后6个月,进行了左乳腺区段切除术和腋窝淋巴结清扫术。给予辅助性FEC化疗,随后进行放疗。在16个月的随访期内未检测到疾病复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9fc/5890479/c0518e6a11e3/rjy041f01.jpg

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