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直径小于 10 毫米的结直肠肿瘤病理诊断相关挑战。

Challenges associated with the pathological diagnosis of colorectal tumors less than 10 mm in size.

机构信息

Department of Surgical Pathology, Sapporo Kosei General Hospital, Sapporo, Japan.

Division of Research and Development for Minimally Invasive Treatment, Cancer Center, School of Medicine, Keio University, Tokyo, Japan.

出版信息

Dig Endosc. 2018 Apr;30 Suppl 1:41-44. doi: 10.1111/den.13038.

DOI:10.1111/den.13038
PMID:29658649
Abstract

Various techniques including cold snare polypectomy and endoscopic mucosal resection are used for the removal of small colorectal polyps. Specimens of resected polyps are prepared in pathology laboratories and analyzed to make a pathological diagnosis. However, reports on how different resection methods influence the pathological diagnosis are limited. This article discusses the problems associated with the failure of polyp retrieval and fragmentation of small specimens during collection and the effects of certain parameters on the pathological diagnosis, particularly with regard to surgical margins. In the future, although pathologists are expected to encounter problems as a result of minor findings that are not clinically problematic, relatively rare cases such as submucosal invasion by a small carcinoma should not be overlooked.

摘要

各种技术,包括冷圈套息肉切除术和内镜黏膜切除术,用于切除小的结直肠息肉。切除的息肉标本在病理实验室进行准备和分析,以做出病理诊断。然而,关于不同的切除方法如何影响病理诊断的报告是有限的。本文讨论了在收集过程中息肉丢失和小标本碎裂相关的问题,以及某些参数对病理诊断的影响,特别是手术切缘。在未来,尽管病理学家可能会因为没有临床问题的微小发现而遇到问题,但也不应忽视相对罕见的情况,如小癌的黏膜下浸润。

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