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向 Marcelle Grenson(1925-1996)致敬,她是酵母中氨基酸转运研究的先驱。

Tribute to Marcelle Grenson (1925-1996), A Pioneer in the Study of Amino Acid Transport in Yeast.

机构信息

Molecular Physiology of the Cell, Université Libre de Bruxelles (ULB), Biopark, 6041 Gosselies, Belgium.

出版信息

Int J Mol Sci. 2018 Apr 16;19(4):1207. doi: 10.3390/ijms19041207.

DOI:10.3390/ijms19041207
PMID:29659503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5979419/
Abstract

The year 2016 marked the 20th anniversary of the death of Marcelle Grenson and the 50th anniversary of her first publication on yeast amino acid transport, the topic to which, as Professor at the Free University of Brussels (ULB), she devoted the major part of her scientific career. M. Grenson was the first scientist in Belgium to introduce and apply genetic analysis in yeast to dissect the molecular mechanisms that were underlying complex problems in biology. Today, M. Grenson is recognized for the pioneering character of her work on the diversity and regulation of amino acid transporters in yeast. The aim of this tribute is to review the major milestones of her forty years of scientific research that were conducted between 1950 and 1990.

摘要

2016 年是 Marcelle Grenson 逝世 20 周年和她首次发表关于酵母氨基酸运输论文 50 周年,作为布鲁塞尔自由大学(ULB)的教授,她将其科学生涯的大部分时间都投入到这一主题的研究中。M. Grenson 是比利时首位在酵母中引入和应用遗传分析来剖析生物学复杂问题背后的分子机制的科学家。如今,M. Grenson 的开创性工作得到了广泛认可,她研究了酵母中氨基酸转运蛋白的多样性和调控。本文旨在回顾她在 1950 年至 1990 年间进行的 40 年科研工作中的主要里程碑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/6b109be5c8d7/ijms-19-01207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/14e5c9b90d5a/ijms-19-01207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/f4e1a907b6ee/ijms-19-01207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/6b109be5c8d7/ijms-19-01207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/14e5c9b90d5a/ijms-19-01207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/f4e1a907b6ee/ijms-19-01207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0493/5979419/6b109be5c8d7/ijms-19-01207-g003.jpg

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本文引用的文献

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