Division of Research, Kaiser Permanente Northern California, Oakland, CA, United States.
Division of Research, Kaiser Permanente Northern California, Oakland, CA, United States.
Addict Behav. 2018 Sep;84:110-117. doi: 10.1016/j.addbeh.2018.03.033. Epub 2018 Mar 31.
Limited primary care-based research has examined hazardous drinking risk factors and motivation to reduce use in persons with HIV (PWH).
We computed prevalence ratios (PR) for factors associated with recent (<30 days) hazardous alcohol use (i.e., 4+/5+ drinks in a single day for women/men), elevated Alcohol Use Disorders Identification Test (AUDIT) scores, and importance and confidence (1-10 Likert scales) to reduce drinking among PWH in primary care.
Of 614 participants, 48% reported recent hazardous drinking and 12% reported high alcohol use severity (i.e., AUDIT zone 3 or higher). Factors associated with greater alcohol severity included moderate/severe anxiety (PR: 2.07; 95% CI: 1.18, 3.63), tobacco use (PR: 1.79; 1.11, 2.88), and other substance use (PR: 1.72; 1.04, 2.83). Factors associated with lower alcohol severity included age 50-59 years (PR: 0.46; 0.22, 2.00) compared with age 20-39 years, and having some college/college degree (PR: 0.61; 0.38, 0.97) compared with ≤high school. Factors associated with greater importance to reduce drinking (scores >5) included: moderate/severe depression (PR: 1.43; 1.03, 2.00) and other substance use (PR: 1.49; 1.11, 2.01). Lower importance was associated with incomes above $50,000 (PR: 0.65; 0.46, 0.91) and marijuana use (PR: 0.65; 0.49, 0.87). HIV-specific factors (e.g., CD4 and HIV RNA levels) were not associated with alcohol outcomes.
This study identified modifiable participant characteristics associated with alcohol outcomes in PWH, including anxiety and depression severity, tobacco use, and other substance use.
基于初级保健的有限研究已经考察了艾滋病毒感染者(HIV 感染者)中危险饮酒的风险因素和减少饮酒的动机。
我们计算了与近期(<30 天)危险饮酒(即女性/男性每天饮用 4+/5+ 杯酒)、酒精使用障碍识别测试(AUDIT)评分升高以及减少 HIV 感染者饮酒的重要性和信心(1-10 级 Likert 量表)相关的因素在初级保健中 HIV 感染者中的患病率比值(PR)。
在 614 名参与者中,48%报告了近期危险饮酒,12%报告了较高的酒精使用严重程度(即 AUDIT 区 3 或更高)。与更高的酒精严重程度相关的因素包括中度/重度焦虑(PR:2.07;95%CI:1.18,3.63)、吸烟(PR:1.79;1.11,2.88)和其他物质使用(PR:1.72;1.04,2.83)。与较低的酒精严重程度相关的因素包括与 20-39 岁相比,年龄为 50-59 岁(PR:0.46;0.22,2.00),以及具有一些大学/大学学位(PR:0.61;0.38,0.97)相比,高中以下学历。与减少饮酒的重要性较高(得分>5)相关的因素包括:中度/重度抑郁(PR:1.43;1.03,2.00)和其他物质使用(PR:1.49;1.11,2.01)。重要性较低与收入高于 50,000 美元(PR:0.65;0.46,0.91)和大麻使用(PR:0.65;0.49,0.87)有关。艾滋病毒特异性因素(例如 CD4 和 HIV RNA 水平)与酒精结果无关。
这项研究确定了与 HIV 感染者酒精相关结果相关的可改变的参与者特征,包括焦虑和抑郁严重程度、吸烟和其他物质使用。