Daugirdas J T, Ing T S
Hines-Loyola Medical Center, Illinois.
Kidney Int Suppl. 1988 Mar;24:S37-43.
We believe that it is worthwhile to separate out two distinct types of first-use reactions: a hypersensitivity type (type A) characterized by anaphylactic signs and symptoms and a non-specific type (type B) characterized primarily by chest pain and back pain. Further research is needed to better define the etiology, the epidemiology, and the pathogenesis of these two subgroups of the first-use syndrome.
我们认为，区分两种不同类型的首次使用反应是值得的：一种是过敏反应型（A型），其特征为过敏体征和症状；另一种是非特异性反应型（B型），其主要特征为胸痛和背痛。需要进一步研究以更好地界定首次使用综合征这两个亚组的病因、流行病学及发病机制。
