Univ. Bordeaux, SANPSY, USR 3413, F-33000, Bordeaux, France.
CNRS-SANPSY, USR 3413, F-33000, Bordeaux, France.
J Sleep Res. 2019 Apr;28(2):e12677. doi: 10.1111/jsr.12677. Epub 2018 Apr 17.
Virtual reality and simulation tools enable us to assess daytime functioning in environments that simulate real life as close as possible. Simulator sickness, however, poses a problem in the application of these tools, and has been related to pre-existing health problems. How sleep problems contribute to simulator sickness has not yet been investigated. In the current study, 20 female chronic insomnia patients and 32 female age-matched controls drove in a driving simulator covering realistic city, country and highway scenes. Fifty percent of the insomnia patients as opposed to 12.5% of controls reported excessive simulator sickness leading to experiment withdrawal. In the remaining participants, patients with insomnia showed overall increased levels of oculomotor symptoms even before driving, while nausea symptoms further increased after driving. These results, as well as the realistic simulation paradigm developed, give more insight on how vestibular and oculomotor functions as well as interoceptive functions are affected in insomnia. Importantly, our results have direct implications for both the actual driving experience and the wider context of deploying simulation techniques to mimic real life functioning, in particular in those professions often exposed to sleep problems.
虚拟现实和模拟工具使我们能够评估尽可能接近真实生活环境中的日间功能。然而，模拟器疾病在这些工具的应用中存在问题，并且与先前存在的健康问题有关。睡眠问题如何导致模拟器疾病尚未得到调查。在当前的研究中，20 名女性慢性失眠患者和 32 名女性年龄匹配的对照者在驾驶模拟器中行驶，模拟了真实的城市、乡村和高速公路场景。与 12.5%的对照组相比，有 50%的失眠患者报告出现过度的模拟器疾病，导致实验退出。在其余参与者中，失眠患者即使在驾驶前也表现出总体上增加的眼球运动症状，而恶心症状在驾驶后进一步增加。这些结果以及开发的现实模拟范式，使我们更深入地了解了在失眠中前庭和眼球运动功能以及内脏感觉功能如何受到影响。重要的是，我们的结果对实际驾驶体验以及更广泛地利用模拟技术来模拟真实生活功能具有直接影响，特别是在那些经常面临睡眠问题的职业中。
