使用2种动物对工业用三亚乙基四胺中存在的4种多胺的致敏潜力进行评估。
Evaluation of the sensitising potential of 4 polyamines present in technical triethylenetetramine using 2 animal species.
作者信息
Maisey J, Purchase R, Robbins M C, Miller K
机构信息
British Industrial Biological Research Association, Carshalton, Surrey, UK.
出版信息
Contact Dermatitis. 1988 Mar;18(3):133-7. doi: 10.1111/j.1600-0536.1988.tb04498.x.
Contact sensitivity to 4 polyamines present in technical grade triethylenetetramine was investigated using the 'VAA mouse' assay and the guinea pig maximization test (GPMT). The criteria used to assess sensitivity in the GPMT classed all substances as having the same degree of sensitising potential. The mouse assay ranked N-(2-piperazin-1-ylethyl)ethylenediamine as having a significantly greater sensitising potential than the other compounds.
使用“VAA 小鼠”试验和豚鼠最大化试验（GPMT）研究了工业级三亚乙基四胺中存在的 4 种多胺的接触敏感性。在 GPMT 中用于评估敏感性的标准将所有物质归类为具有相同程度的致敏潜力。小鼠试验将 N-(2-哌嗪-1-基乙基)乙二胺的致敏潜力列为明显高于其他化合物。
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