Departments of Pediatrics and Psychiatry, University of Colorado School of Medicine, Aurora, CO; Children's Hospital Colorado, Aurora, CO.
Departments of Pediatrics and Psychiatry, University of Colorado School of Medicine, Aurora, CO.
J Pediatr. 2018 Aug;199:99-105. doi: 10.1016/j.jpeds.2018.03.041. Epub 2018 Apr 16.
To evaluate marijuana use by adolescents and young adults with inflammatory bowel disease (IBD).
This descriptive cross-sectional study of patients seen between December 2015 through June 2017 at Children's Hospital Colorado for IBD enrolled patients 13-23 years of age, independent of marijuana use status. Information obtained consisted of chart review, electronic and interview self-report, and serum cannabinoid levels. Marijuana ever-users were compared with never-users for clinical characteristics and perceptions of risk with use; users provided information on routes, patterns, motivations, and perceived benefits and problems with use.
Of 99 participants, ever-use was endorsed by 32% (32 of 99) and daily or almost daily use by 9% (9 of 99). Older age was the only characteristic related to endorsing marijuana use. Twenty-nine ever-users completed all questionnaires. After adjusting for age, users were 10.7 times more likely to perceive low risk of harm with regular use (P < .001). At least 1 medical reason for use was endorsed by 57% (17 of 30), most commonly for relief of physical pain (53%, 16 of 30) (2 did not complete all questionnaires). Problems from use were identified by 37% (11 of 30), most commonly craving/strong urge to use. Most common route of use was smoking (83%) followed by edibles (50%), dabbing (40%), and vaping (30%).
Marijuana use by adolescents and young adults with IBD is common and perceived as beneficial. Guidelines for screening, testing, and counseling of marijuana use should be developed for patients with IBD.
评估青少年和年轻成人炎症性肠病(IBD)患者的大麻使用情况。
这是一项描述性的横断面研究,于 2015 年 12 月至 2017 年 6 月期间在科罗拉多儿童医院就诊的 IBD 患者中招募了 13-23 岁的患者,不论大麻使用情况如何。获取的信息包括病历回顾、电子和访谈自我报告以及血清大麻素水平。曾使用者与从未使用者在临床特征和使用风险认知方面进行比较;使用者提供了使用途径、模式、动机以及对使用的好处和问题的看法。
在 99 名参与者中,32%(32/99)曾使用过大麻,9%(9/99)每天或几乎每天使用。年龄较大是唯一与大麻使用有关的特征。29 名曾使用者完成了所有问卷。调整年龄后,使用者认为定期使用大麻危害低的可能性是未使用者的 10.7 倍(P<.001)。至少有 1 个使用大麻的医学原因被 57%(17/30)的人认可,最常见的原因是缓解身体疼痛(53%,16/30)(2 人未完成所有问卷)。37%(11/30)的人认为使用大麻有问题,最常见的是渴望/强烈的使用欲望。最常见的使用途径是吸烟(83%),其次是食用(50%)、涂抹(40%)和蒸气吸入(30%)。
青少年和年轻成人 IBD 患者中,大麻使用较为常见,并被认为是有益的。应该为 IBD 患者制定筛查、检测和咨询大麻使用的指南。