Yousefnezhad Azadeh, Pirdehghan Azar, Roshandel Rad Mahboubeh, Eskandari Aemeh, Ahmadi Shahnaz
Emam Khomaini Hospital, Tehran University of Medical Science, Tehran, Iran.
Department of Community Medicine, Hamadan University of Medical Science, Hamadan, Iran.
Int J Reprod Biomed. 2018 Jan;16(1):31-34.
Various treatments have been proposed to treat ectopic pregnancy, but their impact on future pregnancies is still the subject of controversy.
The aim of this study is to compare the medical and surgical treatment methods and their impact on the subsequent fertility results and complications in women with a history of ectopic pregnancy.
In this analytical, cross-sectional study, 370 women with the history of ectopic pregnancy, (treared with single dose of methotrexate or salpingectomy by laparotomy), that referred to Al-Zahra Hospital, Rasht, Guilan between 2009 to 2013 were enrolled. 147 women responded to the phone call. The age, the number of women that needed to drug for pregnancy, fertility rate and the fertility outcomes were studied.
147 women responded to the call and between them, 114 women tried to get pregnant again after the ectopic pregnancy treatment. They were agreed to the participate in the study. The mean age of the patients was 28.56±5.63 yr. The fertility rates in the medical and the surgical groups were 56.6% and 47.61%, respectively (p=0.141). There were no significant differences in the poor consequences of pregnancy among the two groups; ectopic pregnancy (p=0.605), miscarriage (p=0.605), and prematuredelivery (p=0.648). 15.1% in the medicinal group and two patients 12.5% in the surgical group had received fertility treatment in order to get pregnant (p=0.135). There was no significant difference in two groups.
It seems that surgical treatment depending on the underlying variables of each patient, can be used such as medical treatment, without worrying about its effect on fertility.
已提出多种治疗异位妊娠的方法，但其对未来妊娠的影响仍存在争议。
本研究旨在比较药物治疗和手术治疗方法及其对有异位妊娠史女性后续生育结果和并发症的影响。
在这项分析性横断面研究中，纳入了2009年至2013年间转诊至吉兰省拉什特市阿尔扎赫拉医院的370例有异位妊娠史（接受单剂量甲氨蝶呤治疗或剖腹输卵管切除术）的女性。147名女性接听了电话。研究了年龄、妊娠所需药物治疗的女性数量、生育率和生育结局。
147名女性接听了电话，其中114名女性在异位妊娠治疗后试图再次怀孕。她们同意参与研究。患者的平均年龄为28.56±5.63岁。药物治疗组和手术治疗组的生育率分别为56.6%和47.61%（p = 0.141）。两组妊娠不良后果无显著差异；异位妊娠（p = 0.605）、流产（p = 0.605）和早产（p = 0.648）。药物治疗组中有15.1%的女性和手术治疗组中有2名患者（12.5%）接受了生育治疗以实现怀孕（p = 0.135）。两组之间无显著差异。
似乎根据每位患者的潜在变量，手术治疗可以像药物治疗一样使用，而不必担心其对生育能力的影响。
