Division of Nephrology and Hypertension, University Hospitals Cleveland Medical Center, Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Curr Cardiol Rep. 2018 Apr 19;20(6):41. doi: 10.1007/s11886-018-0991-x.
Central blood pressure is a novel predictor of cardiovascular risk that can be measured in the clinical setting using currently available technology. This paper will review current available methods of central blood pressure monitoring as well as its impact in cardiac and renal disease.
Both aortic and carotid systolic blood pressure are independently associated with cardiovascular mortality and serious cardiac events. Furthermore, studies show that systolic aortic blood pressure has been shown to be superior predictor of cardiovascular as compared to brachial blood pressure. Inhibitors of the renin angiotensin axis may have a beneficial effect on central blood pressure; however, long term studies evaluating the impact of lowering central blood pressure on clinical outcomes are lacking. Central blood pressure is a good predictor of cardiovascular risk. As more studies emerge demonstrating the value of central blood pressure as a therapeutic target, it is possible that targeting central blood pressure may become an important part of the armamentarium to lower cardiovascular risk.
中心血压是心血管风险的一种新的预测指标,可以使用当前可用的技术在临床环境中进行测量。本文将综述目前中心血压监测的可用方法及其在心、肾疾病中的作用。
主动脉和颈动脉收缩压均与心血管死亡率和严重心脏事件独立相关。此外,研究表明,与肱动脉血压相比,主动脉收缩压更能预测心血管疾病。肾素-血管紧张素轴抑制剂可能对中心血压有有益的影响;然而,缺乏评估降低中心血压对临床结局影响的长期研究。中心血压是心血管风险的良好预测指标。随着越来越多的研究表明中心血压作为治疗靶点的价值,将中心血压作为治疗靶点可能成为降低心血管风险的重要手段之一。