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韩国中重度特应性皮炎的当前管理:对韩国过敏症专科医生、儿科过敏症专科医生和皮肤科医生的一项调查。

Current Management of Moderate-to-Severe Atopic Dermatitis: A Survey of Allergists, Pediatric Allergists and Dermatologists in Korea.

作者信息

Yum Hye Yung, Kim Hyun Hee, Kim Hyun Jung, Kim Woo Kyung, Lee So Yeon, Li Kapsok, Lee Dong Hun

机构信息

Department of Pediatrics, Seoul Medical Center, Seoul, Korea.

Department of Dermatology, Seoul Medical Center, Seoul, Korea.

出版信息

Allergy Asthma Immunol Res. 2018 May;10(3):253-259. doi: 10.4168/aair.2018.10.3.253.

Abstract

PURPOSE

There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians' specialties, we collected data on the current treatment approach to moderate-to-severe AD among allergists, pediatric allergists and dermatologists in Korea.

METHODS

This questionnaire-based study was administered to physicians from the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI), Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD), and Korean Atopic Dermatitis Association (KADA).

RESULTS

A total of 93 physicians participated in the study; 64.5% were pediatric allergists and 31.2% were dermatologists. The major patient age groups were "less than 5 years" for 100% of pediatric allergists and "6-12 years old" for 38% of dermatologists. The proportion of patients with moderate-to-severe AD was higher for dermatologists and allergists compared to pediatric allergists. Physicians agreed on the necessity of education including demonstration of basic skin care and application of topical therapies (88.2%), nutritional consultation (83.9%) and psychological counseling (75.3%). However, less than half were able to educate and counsel their patients in real practice. There were noticeable differences in first-line treatment among physician groups. For pediatric allergists, the order of preferred systemic treatment was wet wrap therapy, systemic corticosteroids and oral cyclosporin. Dermatologists ranked cyclosporin, phototherapy, and systemic corticosteroids as first-line treatment regimens. Major reported barriers to proper management were steroid phobia, unproven complementary and alternative medicine, lack of education, and the unreasonable insurance system.

CONCLUSIONS

Our findings suggest there are distinct differences in moderate-to-severe AD treatment according to physicians' specialties. Medical policy changes along with governmental supports are required in order to implement the ideal approach in real practice. For moderate-to-severe AD, a consensus on the approach to optimal management should be reached for the best outcomes, based on further randomized controlled trials.

摘要

目的

中重度特应性皮炎(AD)的治疗需求尚未得到满足,导致管理策略存在差异。为了根据医生的专业调查不同的特征和治疗方式,我们收集了韩国过敏症专科医生、儿科过敏症专科医生和皮肤科医生对中重度AD当前治疗方法的数据。

方法

这项基于问卷的研究面向韩国哮喘、过敏与临床免疫学会(KAAACI)、韩国儿科过敏与呼吸疾病学会(KAPARD)以及韩国特应性皮炎协会(KADA)的医生进行。

结果

共有93名医生参与了该研究;64.5%为儿科过敏症专科医生,31.2%为皮肤科医生。主要患者年龄组中,100%的儿科过敏症专科医生面对的是“5岁以下”患者,38%的皮肤科医生面对的是“6 - 12岁 ”患者。与儿科过敏症专科医生相比,皮肤科医生和过敏症专科医生治疗的中重度AD患者比例更高。医生们一致认为教育很有必要,包括基本皮肤护理演示和局部治疗应用(88.2%)、营养咨询(83.9%)以及心理咨询(75.3%)。然而,实际能够对患者进行教育和咨询的医生不到一半。医生群体之间一线治疗存在显著差异。对于儿科过敏症专科医生,首选的全身治疗顺序是湿敷疗法、全身用皮质类固醇和口服环孢素。皮肤科医生将环孢素、光疗和全身用皮质类固醇列为一线治疗方案。报告的正确管理的主要障碍是类固醇恐惧症、未经证实的补充和替代医学、缺乏教育以及不合理 的保险制度。

结论

我们的研究结果表明,根据医生的专业不同,中重度AD的治疗存在明显差异。为了在实际中实施理想的治疗方法,需要改变医疗政策并获得政府支持。对于中重度AD,应基于进一步的随机对照试验,就最佳管理方法达成共识以获得最佳结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e9f/5911444/c2a3491fbd94/aair-10-253-g001.jpg

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