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钙化性皮肤病变累及泪小点和泪点周围组织。

Lacrimal punctal and peripunctal involvement in calcinosis cutis.

机构信息

Govindram Seksaria Institute of Dacryology, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Hygeia Hospital, Athens, Greece.

出版信息

Indian J Ophthalmol. 2018 May;66(5):720-722. doi: 10.4103/ijo.IJO_1185_17.

DOI:10.4103/ijo.IJO_1185_17
PMID:29676330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5939178/
Abstract

Calcinosis cutis is a rare metabolic disorder characterized by cutaneous and subcutaneous deposition of insoluble calcium salts. Ocular adnexal involvement is uncommon but mostly seen in males and in the upper eyelid. Solitary lesions are more common than multiple. The treatment of choice is excision biopsy. Histopathological examination provides a definitive diagnosis. Directed systemic investigations help to rule out underlying pathologies and aids further management. The present case reports the punctal and peripunctal involvement in a case of ocular adnexal calcinosis cutis.

摘要

皮肤钙质沉着症是一种罕见的代谢性疾病，其特征是皮肤和皮下组织中不可溶性钙盐的沉积。眼附属器受累并不常见，但多见于男性和上眼睑。单发皮损比多发皮损更为常见。治疗方法首选切除活检。组织病理学检查可明确诊断。有针对性的系统检查有助于排除潜在的病理，并有助于进一步的治疗。本病例报告了一例眼附属器钙质沉着症中泪小点和泪小点周围受累的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cb/5939178/b1819d54b51d/IJO-66-720-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cb/5939178/1cee9be8dcfc/IJO-66-720-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cb/5939178/b1819d54b51d/IJO-66-720-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cb/5939178/1cee9be8dcfc/IJO-66-720-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cb/5939178/b1819d54b51d/IJO-66-720-g002.jpg

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本文引用的文献

1
Subepidermal Calcinosis in the Ocular Adnexa: A Systematic Review.眼附属器的表皮下钙化症：一项系统评价
Ophthalmic Plast Reconstr Surg. 2018 Mar/Apr;34(2):101-105. doi: 10.1097/IOP.0000000000000936.
2
Calcinosis cutis: part II. Treatment options.皮肤钙化病：第二部分。治疗选择。
J Am Acad Dermatol. 2011 Jul;65(1):15-22; quiz 23-4. doi: 10.1016/j.jaad.2010.08.039.
3
Calcinosis cutis: part I. Diagnostic pathway.皮肤钙化病：第一部分。诊断途径。
J Am Acad Dermatol. 2011 Jul;65(1):1-12; quiz 13-4. doi: 10.1016/j.jaad.2010.08.038.
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Ocular tumoral calcinosis. A clinicopathologic study.
Arch Ophthalmol. 1996 Mar;114(3):341-5. doi: 10.1001/archopht.1996.01100130337022.
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Tumoral calcinosis: seasonal biochemical studies and chemical studies of eyelid lesion.肿瘤性钙化：眼睑病变的季节性生化研究及化学研究
Clin Chem. 1989 Jan;35(1):183-5.