Stringer D A, Sprigg A, Juodis E, Corey M, Daneman A, Levison H J, Durie P R
Department of Radiology, Hospital for Sick Children, Toronto.
Can Assoc Radiol J. 1988 Jun;39(2):100-2.
Between 1971 and 1984, 57 patients with cystic fibrosis (CF) and clinically suspected gastroesophageal reflux (GER) underwent a barium-meal examination and routine pulmonary function testing. Reflux was demonstrated in 18 patients; in six of these it was complicated by hiatus hernia, esophagitis, or stricture formation. Compared with 412 CF patients without known GER, the 18 patients with demonstrable reflux had significantly reduced forced expiratory volume and forced vital capacity. GER should be looked for carefully on any barium-meal study in patients with CF; these patients have an increased incidence of reflux, with its implications for lung function, and are not good candidates for surgical intervention.
1971年至1984年间，57例患有囊性纤维化（CF）且临床怀疑有胃食管反流（GER）的患者接受了钡餐检查和常规肺功能测试。18例患者显示有反流；其中6例并发食管裂孔疝、食管炎或狭窄形成。与412例无已知GER的CF患者相比，18例有明显反流的患者其用力呼气量和用力肺活量显著降低。在对CF患者进行的任何钡餐检查中都应仔细查找GER；这些患者反流发生率增加，对肺功能有影响，且不是手术干预的合适人选。
