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心脏手术后重症监护病房患者住院时间的预测:基于心脏手术死亡率风险计算器EuroSCORE的逻辑回归分析

Prediction of Patient Length of Stay on the Intensive Care Unit Following Cardiac Surgery: A Logistic Regression Analysis Based on the Cardiac Operative Mortality Risk Calculator, EuroSCORE.

作者信息

Meadows Katherine, Gibbens Richard, Gerrard Caroline, Vuylsteke Alain

机构信息

School of Clinical Medicine, University of Cambridge, Cambridge, UK.

Computer Laboratory, University of Cambridge, Cambridge, UK.

出版信息

J Cardiothorac Vasc Anesth. 2018 Dec;32(6):2676-2682. doi: 10.1053/j.jvca.2018.03.007. Epub 2018 Mar 7.

Abstract

OBJECTIVE

The aim of this study was to develop a statistical model based on patient parameters to predict the length of stay (LOS) in the intensive care unit (ICU) following cardiac surgery in a single center.

DESIGN

Data were collected from patients admitted to the ICU following cardiac surgery over a 10-year period (2006-2016). Both the additive and logistic EuroSCORE were calculated, and logistic regression analysis was carried out to formulate a model relating the predicted LOS to the EuroSCORE. This model was used to stratify patients into short stay (less than 48 hours) or long stay (more than 48 hours).

SETTING

ICU at Papworth Hospital, Cambridgeshire.

PARTICIPANTS

A total of 18,377 consecutive patients who had been in ICU following cardiac surgery (coronary graft bypass surgery, valve surgery, or a combination of both).

INTERVENTIONS

This was an observational study.

MEASUREMENTS AND MAIN RESULTS

The authors have shown that both the additive and logistic EuroSCORE can be used to stratify cardiac surgical patients in various predicted LOS in ICU. Further adjustments can be made to increase the number of patients correctly identified as either short stay or long stay. Comparison of the model predictions to the data demonstrated a high overall accuracy of 79.77%, and receiver operating characteristic curve analysis showed the area under the curve to be 0.7296.

CONCLUSION

This analysis of an extensive data set shows that patient LOS in ICU after cardiac surgery in a single center can be predicted accurately using the simple cardiac operative risk scoring tool EuroSCORE. Using such predictions has the potential to improve ICU resource management.

摘要

目的

本研究旨在基于患者参数开发一种统计模型,以预测单中心心脏手术后在重症监护病房(ICU)的住院时间(LOS)。

设计

收集了10年期间(2006 - 2016年)心脏手术后入住ICU患者的数据。计算了累加式和逻辑式欧洲心脏手术风险评估系统(EuroSCORE),并进行逻辑回归分析以建立一个将预测的住院时间与EuroSCORE相关联的模型。该模型用于将患者分为短住院时间(少于48小时)或长住院时间(超过48小时)。

地点

剑桥郡帕普沃思医院的ICU。

参与者

共有18377例心脏手术后入住ICU的连续患者(冠状动脉搭桥手术、瓣膜手术或两者联合手术)。

干预措施

这是一项观察性研究。

测量指标及主要结果

作者表明,累加式和逻辑式EuroSCORE均可用于对心脏手术患者在ICU的不同预测住院时间进行分层。可进一步调整以增加正确识别为短住院时间或长住院时间患者的数量。模型预测与数据的比较显示总体准确率较高,为79.77%,受试者工作特征曲线分析显示曲线下面积为0.7296。

结论

对大量数据集的这一分析表明,可以使用简单的心脏手术风险评分工具EuroSCORE准确预测单中心心脏手术后患者在ICU的住院时间。利用此类预测有可能改善ICU资源管理。

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