Chang Hanxiao, Shen Yuqi, Li Zheng, Lin Chao, Chen Hua, Lu Hua
Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Department of Neurosurgery, Jiangsu Province Hospital, Nanjing, China.
Front Neurol. 2021 Apr 8;12:606219. doi: 10.3389/fneur.2021.606219. eCollection 2021.
To summarize and discuss the application of Willis covered stents (WCSs) and double stent-assisted coils in the treatment of blood blister-like aneurysms (BBAs). Thirty-two patients with BBAs treated from January 2015 to October 2020 were included in the study. Among them, 18 were treated using WCSs and 14 using double stents-assisted coils. The indications for treatment, perioperative findings, and postoperative follow-up results were collected and analyzed. All 32 patients had successful stent deployments. Complete aneurysm occlusion was achieved in all 18 patients treated with WCSs immediately. WCS-related adverse events included 2 cases of mild vasospasm and 4 aggressive procedure-related vasospasms during WCS deployment, a case of dissection after WCS deployment, and 1 death due to ipsilateral temporal lobe rebleeding at the sixth day after WCS deployment. In patients treated with double stent-assisted coils, there were 3 cases of neck remnants, 1 acute occlusion of the ipsilateral MCA branch, and 4 mild procedure-related intraoperative vasospasms. The mean follow-up period was 4.2±1.6 months (range 3-6 months). Follow-up imaging data were available for 25 patients (78.1%). In the first postoperative angiographic follow-up, all BBAs were completely occluded. Mild asymptomatic stent stenosis was observed in 3 patients treated with WCSs. Follow-up examination at 6 months after the employment of WCSs showed that the modified Rankin score (mRs) was 0 in 6 patients, 1 in 5 patients, 2 in 3 patients, 3 in 1 patient, 4 in 2 patients, and 6 in 1 patient. After treatment with double stents-assisted coils, the mRs was 0 in 4 patients, 1 in 5 patients, 2 in 3 patients, and 4 in 2 patients. WCSs and double stent-assisted coils for the treatment of BBAs are both safe and efficient. WCSs provide a higher rate of immediate occlusion; however, there was no significant difference in the long term.
总结并讨论Willis覆膜支架(WCS)和双支架辅助弹簧圈在血泡样动脉瘤(BBA)治疗中的应用。本研究纳入了2015年1月至2020年10月期间接受治疗的32例BBA患者。其中,18例采用WCS治疗,14例采用双支架辅助弹簧圈治疗。收集并分析治疗指征、围手术期结果及术后随访结果。所有32例患者支架置入均成功。18例接受WCS治疗的患者均立即实现动脉瘤完全闭塞。与WCS相关的不良事件包括WCS置入期间2例轻度血管痉挛和4例与操作相关的严重血管痉挛、1例WCS置入后夹层,以及1例在WCS置入后第6天因同侧颞叶再出血死亡。在接受双支架辅助弹簧圈治疗的患者中,有3例瘤颈残留、1例同侧大脑中动脉(MCA)分支急性闭塞,以及4例与操作相关的轻度术中血管痉挛。平均随访期为4.2±1.6个月(范围3 - 6个月)。25例患者(78.1%)有随访影像学资料。在术后首次血管造影随访中,所有BBA均完全闭塞。3例接受WCS治疗的患者观察到轻度无症状支架狭窄。采用WCS治疗6个月后的随访检查显示,改良Rankin量表(mRs)评分:6例患者为0分,5例患者为1分,3例患者为2分,1例患者为3分,2例患者为4分,1例患者为6分。采用双支架辅助弹簧圈治疗后,mRs评分:4例患者为0分,5例患者为1分,3例患者为2分,2例患者为4分。WCS和双支架辅助弹簧圈治疗BBA均安全有效。WCS能提供更高的即刻闭塞率;然而,长期来看并无显著差异。