Liu Lun-Xin, Zhang Chang-Wei, Lin Sen, Wu Cong, Wang Ting, Zhou Liang-Xue, Wang Chao-Hua, Xie Xiao-Dong
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
World Neurosurg. 2019 Feb;122:e546-e552. doi: 10.1016/j.wneu.2018.10.098. Epub 2018 Oct 25.
The purpose of this study is to introduce our initial experience with the evaluation of the feasibility of using Willis covered stents (WCSs) in the treatment of complicated ophthalmic artery (OA) segment aneurysms.
Of the 162 patients with OA segment aneurysms treated by endovascular techniques in West China Hospital from January 2015 to August 2017, a total of 26 patients treated with WCSs were included in the study.
Twenty-six patients with 26 aneurysms were included (mean age, 57.0 years; range, 22-76 years). The cohort had 20 patients with large or giant aneurysms, 3 patients with blood blister aneurysms, and 3 patients with pseudoaneurysms. Ten aneurysms were OA type, and 16 were internal carotid artery (ICA) type. Twenty-four patients were treated with 1 stent, and 2 patients were treated with 2 stents. Among the 26 patients, 2 patients had minimal endoleak, and 24 patients had complete occlusion after immediate postoperative angiography. One patient who had complete occlusion experienced contrast agent extravasation, and this phenomenon disappeared by balloon compression during the procedure. The 3- to 15-month angiographic follow-up showed that all patients experienced complete occlusion, including 2 patients with minimal endoleak during immediate postprocedural angiography. Two patient showed signs of in-stent stenosis. Clinical follow-up demonstrated that no delayed thromboembolic or ischemic events were recorded in the stent-grafted vascular region and no bleeding occurred in any of the patients (except 1 patient who experienced subarachnoid hemorrhage, left frontal lobe hemorrhage, and hydrocephalus 10 days after the procedure).
WCSs may provide an alternative solution for treating complex OA segment aneurysms by reconstruction and preservation of the ICA. Our study also confirms the safety, efficacy, and midterm durability of WCSs for complex OA segment aneurysms.
本研究旨在介绍我们在评估使用Willis覆膜支架(WCS)治疗复杂眼动脉(OA)段动脉瘤可行性方面的初步经验。
在2015年1月至2017年8月于华西医院接受血管内技术治疗的162例OA段动脉瘤患者中,共有26例接受WCS治疗的患者纳入本研究。
纳入26例患有26个动脉瘤的患者(平均年龄57.0岁;范围22 - 76岁)。该队列中有20例大型或巨大动脉瘤患者,3例血泡样动脉瘤患者,以及3例假性动脉瘤患者。10个动脉瘤为OA型,16个为颈内动脉(ICA)型。24例患者使用1枚支架治疗,2例患者使用2枚支架治疗。在这26例患者中,2例出现微量内漏,24例在术后即刻血管造影显示完全闭塞。1例完全闭塞的患者出现造影剂外渗,术中通过球囊压迫该现象消失。3至15个月的血管造影随访显示所有患者均完全闭塞,包括2例在术后即刻血管造影时有微量内漏的患者。2例患者出现支架内狭窄迹象。临床随访表明,支架植入血管区域未记录到延迟性血栓栓塞或缺血事件,所有患者均未发生出血(除1例患者在术后10天出现蛛网膜下腔出血、左额叶出血和脑积水)。
WCS可能通过重建和保留ICA为治疗复杂OA段动脉瘤提供一种替代解决方案。我们的研究还证实了WCS治疗复杂OA段动脉瘤的安全性、有效性和中期耐久性。