Culebras-Atienza E, Silvestre F-J, Silvestre-Rangil J
Dentistry and Medicine Faculty, University of Valencia, C/ Gasco Oliag n 1, Valencia 46010, SPAIN,
Med Oral Patol Oral Cir Bucal. 2018 May 1;23(3):e335-e343. doi: 10.4317/medoral.22311.
The present study was carried out to evaluate the possible association between obesity and periodontitis in patients with DS, and to explore which measure of obesity is most closely correlated to periodontitis.
A prospective observational study was made to determine whether obesity is related to periodontal disease in patients with DS. The anthropometric variables were body height and weight, which were used to calculate BMI and stratify the patients into three categories: < 25(normal weight), 25-29.9 (overweight) and ≥ 30.0 kg/m2 (obese). Waist circumference and hip circumference in turn was recorded as the greatest circumference at the level of the buttocks, while the waist/hip ratio (WHR) was calculated. Periodontal evaluation was made of all teeth recording the plaque index (PI), pocket depth (PD), clinical attachment level (CAL) and the gingival index. We generated a multivariate linear regression model to examine the relationship between PD and the frequency of tooth brushing, gender, BMI, WHI, WHR, age and PI.
Significant positive correlations were observed among the anthropometric parameters BMI, WHR, WHI and among the periodontal parameters PI, PD, CAL and GI. The only positive correlation between the anthropometric and periodontal parameters corresponded to WHR. Upon closer examination, the distribution of WHR was seen to differ according to gender. Among the women, the correlation between WHR and the periodontal variables decreased to nonsignificant levels. In contrast, among the males the correlation remained significant and even increased. In a multivariate linear regression model, the coefficients relating PD to PI, WHR and age were positive and significant in all cases.
Our results suggest that there may indeed be an association between obesity and periodontitis in male patients with DS. Also, we found a clear correlation with WHR, which was considered to be the ideal adiposity indicator in this context.
本研究旨在评估唐氏综合征（DS）患者肥胖与牙周炎之间可能存在的关联，并探究哪种肥胖指标与牙周炎的相关性最强。
进行一项前瞻性观察性研究，以确定肥胖是否与DS患者的牙周疾病相关。人体测量变量包括身高和体重，用于计算体重指数（BMI）并将患者分为三类：<25（正常体重）、25 - 29.9（超重）和≥30.0 kg/m²（肥胖）。依次记录腰围和臀围，以臀部水平处最大周长为准，同时计算腰臀比（WHR）。对所有牙齿进行牙周评估，记录菌斑指数（PI）、牙周袋深度（PD）、临床附着水平（CAL）和牙龈指数。我们建立了一个多元线性回归模型，以研究PD与刷牙频率、性别、BMI、腰高指数（WHI）、WHR、年龄和PI之间的关系。
在人体测量参数BMI、WHR、WHI之间以及牙周参数PI、PD、CAL和GI之间观察到显著的正相关。人体测量参数与牙周参数之间唯一的正相关对应于WHR。进一步检查发现，WHR的分布因性别而异。在女性中，WHR与牙周变量之间的相关性降至无显著意义的水平。相比之下，在男性中，相关性仍然显著甚至有所增加。在多元线性回归模型中，PD与PI、WHR和年龄相关的系数在所有情况下均为正且显著。
我们的结果表明，DS男性患者中肥胖与牙周炎之间可能确实存在关联。此外，我们发现与WHR存在明显相关性，在这种情况下WHR被认为是理想的肥胖指标。
