Division of Preventive Dentistry, Department of Oral Health Science, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-Dori, Chuo-Ku, Niigata 951-8514, Japan.
Public Health Nutr. 2013 Feb;16(2):330-8. doi: 10.1017/S1368980012002637. Epub 2012 May 22.
To investigate the longitudinal relationship between the intake of dietary antioxidants and periodontal disease in community-dwelling older Japanese.
A retrospective cohort study, with a follow-up of 2 years (2003-2005). Intakes of dietary antioxidants (vitamin C, vitamin E, α-carotene and β-carotene) were assessed with a validated FFQ. Participants were classified by tertile of antioxidant intake. Full-mouth periodontal status, measured as the clinical attachment level, was recorded at baseline and follow-up examinations. Periodontal disease progression was considered as loss of attachment of 3 mm or greater over the study period at the interproximal site for each tooth. Finally, the number of teeth with periodontal disease progression per person was calculated and was used as the outcome. Poisson regression analysis was conducted, with dietary antioxidants as the main exposure, to estimate their influence on the number of teeth with periodontal disease progression.
Niigata City (Japan).
Dentate individuals aged 75 years in 2003, for whom data were available, were included in the analyses (n 264).
A higher intake of dietary antioxidants was inversely associated with the number of teeth with periodontal disease progression, controlling for other variables. The multivariate-adjusted incidence rate ratios in the first, second and third tertiles were 1·00, 0·76 (95 % CI 0·60, 0·97) and 0·72 (95 % CI 0·56, 0·93) for vitamin C; 1·00, 0·79 (95 % CI 0·62, 0·99) and 0·55 (95 % CI 0·42, 0·72), for vitamin E; and 1·00, 1·02 (95 % CI 0·81, 1·29) and 0·73 (95 % CI 0·56, 0·95) for β-carotene.
The study results suggest that higher intake of antioxidants may mitigate periodontal disease in community-dwelling older Japanese.
调查社区居住的日本老年人饮食抗氧化剂摄入量与牙周病之间的纵向关系。
一项回顾性队列研究，随访时间为 2 年（2003-2005 年）。采用验证过的食物频率问卷评估饮食抗氧化剂（维生素 C、维生素 E、α-胡萝卜素和β-胡萝卜素）的摄入量。参与者按抗氧化剂摄入量的三分位进行分类。在基线和随访检查时，记录全口牙周状况，以临床附着水平衡量。牙周病的进展被定义为在研究期间每个牙齿近中部位的附着丧失 3 毫米或更多。最后，计算每个人患有牙周病进展的牙齿数，并将其作为结果。采用 Poisson 回归分析，以饮食抗氧化剂为主要暴露因素，估计其对患有牙周病进展的牙齿数的影响。
日本新潟市。
2003 年年龄在 75 岁以上且有数据可用的有牙个体被纳入分析（n=264）。
在控制其他变量后，饮食抗氧化剂摄入量较高与患有牙周病进展的牙齿数呈负相关。在第一、第二和第三三分位组中，维生素 C 的多变量校正发病率比分别为 1.00、0.76（95%CI 0.60，0.97）和 0.72（95%CI 0.56，0.93）；维生素 E 分别为 1.00、0.79（95%CI 0.62，0.99）和 0.55（95%CI 0.42，0.72）；β-胡萝卜素分别为 1.00、1.02（95%CI 0.81，1.29）和 0.73（95%CI 0.56，0.95）。
研究结果表明，较高的抗氧化剂摄入量可能减轻社区居住的日本老年人的牙周病。
