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英夫利昔单抗治疗红皮病型银屑病的计算机断层扫描成像结果:病例报告

Computed tomography imaging findings in erythrodermic psoriasis treated with infliximab: A case report.

作者信息

Kurokawa Ryo, Hagiwara Akifumi, Niijima Yasuko, Kojima Kaoru

机构信息

Department of Radiology, Toshiba Hospital, Oimachi, Tokyo, 6-3-22 Oimachi, Shinagawa-ku, Tokyo 140-8522, Japan.

Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

Radiol Case Rep. 2018 Mar 2;13(2):460-463. doi: 10.1016/j.radcr.2018.02.005. eCollection 2018 Apr.

Abstract

Erythrodermic psoriasis (EP), 1 of the most rare and severe forms of psoriasis, is characterized by general erythema with silvery scales. Systemic vasodilatation in EP is potentially life-threatening, however, the degree and extent of inflammation in subcutaneous tissues are difficult to estimate accurately using standard skin inspections or ultrasound examinations. Computed tomography can be a useful modality in solving this problem. The authors report a case of EP. Sequential contrast-enhanced whole-body computed tomography before and after treatment with a tumor necrosis factor-α inhibitor (infliximab) visualized the inflammation and the effect of the treatment.

摘要

红皮病型银屑病(EP)是银屑病最罕见、最严重的形式之一,其特征为全身性红斑伴银色鳞屑。EP中的全身血管扩张有潜在生命危险,然而,使用标准的皮肤检查或超声检查难以准确估计皮下组织炎症的程度和范围。计算机断层扫描在解决这一问题上可能是一种有用的方式。作者报告了一例EP病例。在用肿瘤坏死因子-α抑制剂(英夫利昔单抗)治疗前后进行的序列对比增强全身计算机断层扫描显示了炎症及治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9521/5906861/c03229375b0f/radcr456-fig-0001.jpg

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