Lo Yang, Tsai Tsen-Fang
Department of Dermatology, Cathay General Hospital, Taipei, Taiwan.
Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Psoriasis (Auckl). 2021 Jun 9;11:59-73. doi: 10.2147/PTT.S288345. eCollection 2021.
Erythrodermic psoriasis (EP) is a rare variant of psoriasis, which is potentially life threatening and often resistant to conventional therapy. Biologics have revolutionized the treatment of plaque-type psoriasis, and shown promise in EP. However, due to the lack of head-to-head studies and the rarity of EP, no high level evidence-based treatment guidelines for EP have been established, and the evidence of treatment of EP is limited to case reports or small case series. Here, we present a narrative review focusing on the up-to-date information for the treatment of EP.
红皮病型银屑病(EP)是银屑病的一种罕见变体,具有潜在的生命威胁,且常常对传统治疗耐药。生物制剂彻底改变了斑块型银屑病的治疗方式,并在红皮病型银屑病治疗中显示出前景。然而,由于缺乏头对头研究以及红皮病型银屑病的罕见性,尚未建立基于高级别证据的红皮病型银屑病治疗指南,红皮病型银屑病的治疗证据仅限于病例报告或小型病例系列。在此,我们进行一项叙述性综述,重点关注红皮病型银屑病治疗的最新信息。