全秃与溃疡性结肠炎及硫唑嘌呤的作用
Alopecia Universalis Associated with Ulcerative Colitis and The Role of Azathioprine.
作者信息
Shohdy Kyrillus S, Rashad Wegdan, Elmeligui Ahmed
机构信息
Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
出版信息
Middle East J Dig Dis. 2018 Jan;10(1):50-54. doi: 10.15171/mejdd.2017.91. Epub 2018 Jan 12.
Abstract
Skin manifestations can herald, co-exist, or follow the evolution of inflammatory bowel disease (IBD). We report a middle-aged man with recent onset alopecia universalis and a history of intermittent diarrheal attacks for 6 years. Colonscopy and biopsy sampling confirmed ulcerative colitis. Regrowth of hair was achieved by treating the patient with azathioprine and mesalamine. Clinicians have to be aware that a multitude of skin manifestations with history of diarrhea can be an extraintestinal manifestation of IBD such as ulcerative colitis and this warrants further investigation.
摘要
皮肤表现可能先于、与炎症性肠病（IBD）同时出现或在其病程中出现。我们报告了一名中年男性，近期出现全秃，并有6年间歇性腹泻发作史。结肠镜检查和活检取样证实为溃疡性结肠炎。通过使用硫唑嘌呤和美沙拉嗪治疗该患者，实现了毛发再生。临床医生必须意识到，有腹泻病史的多种皮肤表现可能是IBD（如溃疡性结肠炎）的肠外表现，这值得进一步调查。
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