National Medical College, Birgunj, Parsa, Nepal.
Nepal Police Hospital, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Sep 11;59(241):935-937. doi: 10.31729/jnma.5830.
Alopecia universalis is an uncommon form of alopecia areata involving hair loss over the entire scalp and body. This condition is difficult to treat and sustain the growth of hair for longer duration. We report a case of alopecia universalis associated with severe hyperthyroidism. A lady in her fourth decade presented to us with gradual onset of alopecia universalis, who later found to have hyperthyroidism which was refractory to multiple treatment modalities. She was treated successfully with azathioprine and hydroxychloroquine. Alopecia universalis with less response to oral steroid therapy was successfully managed with azathioprine with hydroxychloroquine.
全身性脱发是一种罕见的斑秃形式,涉及整个头皮和全身的毛发脱落。这种情况很难治疗,并且难以长时间维持头发生长。我们报告一例与严重甲状腺功能亢进相关的全身性脱发。一位四十多岁的女性逐渐出现全身性脱发,后来发现患有甲状腺功能亢进症,且对多种治疗方法均有抗性。她成功地接受了硫唑嘌呤和羟氯喹治疗。全身性脱发对口服类固醇治疗反应不佳,成功地接受了硫唑嘌呤联合羟氯喹治疗。