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胸腹主动脉瘤杂交修复术:未来已来?

Hybrid thoracoabdominal aortic aneurysm repair: is the future here?

作者信息

Orozco-Sevilla Vicente, Weldon Scott A, Coselli Joseph S

机构信息

Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.

Section of Adult Cardiac Surgery, Texas Heart Institute, Houston, Texas, USA.

出版信息

J Vis Surg. 2018 Mar 30;4:61. doi: 10.21037/jovs.2018.02.14. eCollection 2018.

Abstract

Open surgical repair has been the gold standard for thoracoabdominal aortic aneurysm (TAAA) repair for more than 6 decades, but 2 additional options have emerged: total endovascular TAAA repair and a hybrid approach that combines open and endovascular repair. Despite the optimism for an endovascular approach, long-term results for these repairs are still lacking. Some of the issues with this emerging technology include the risk of paraplegia after extensive endovascular repair, the need for multiple reinterventions, continuous stent-graft surveillance, endograft branch stenosis, as well as the significant learning curve. Interest in a hybrid approach has resurged despite the non-superior results compared to open TAAA. Commonly, the focus of the hybrid approach is now on performing a less extensive open TAAA repair, which is then extended with a stent-graft or vice versa. Moreover, this approach is now often performed in two stages in an effort to decrease the associated spinal cord ischemia. Open surgical repair after endovascular aortic repair is increasingly being performed to address serious complications, such as infection or fistula, that cannot be repaired by further endovascular intervention. As with any new technology, there will be an increase in the number of procedure-related complications and a decrease in the number of surgeons who can perform the traditional open operation with good results.

摘要

六十多年来,开放手术修复一直是胸腹主动脉瘤(TAAA)修复的金标准,但现在又出现了另外两种选择:完全腔内TAAA修复以及一种将开放手术与腔内修复相结合的杂交手术方式。尽管人们对腔内手术方式充满乐观,但这些修复方式的长期效果仍然缺乏。这项新兴技术存在的一些问题包括广泛腔内修复后发生截瘫的风险、需要多次再次干预、持续的支架移植物监测、腔内移植物分支狭窄,以及显著的学习曲线。尽管与开放TAAA手术相比,杂交手术方式的效果并不更优,但人们对它的兴趣再度兴起。通常,杂交手术方式现在的重点是进行范围较小的开放TAAA修复,然后用支架移植物进行扩展,反之亦然。此外,这种手术方式现在常常分两个阶段进行,以努力减少相关的脊髓缺血。在腔内主动脉修复后进行开放手术修复越来越多地用于处理诸如感染或瘘等严重并发症,这些并发症无法通过进一步的腔内干预来修复。与任何新技术一样,与手术相关的并发症数量将会增加,而能够成功实施传统开放手术的外科医生数量将会减少。

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