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伊朗伊拉姆市自来水中金属(类)的致癌和非致癌健康风险。

Carcinogenic and non-carcinogenic health risks of metal(oid)s in tap water from Ilam city, Iran.

机构信息

Department of Environmental Health Engineering, Student Research Committee, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

School of Earth and Environmental Sciences, The University of Queensland, Queensland, Australia.

出版信息

Food Chem Toxicol. 2018 Aug;118:204-211. doi: 10.1016/j.fct.2018.04.039. Epub 2018 Apr 20.

Abstract

One of the most important pathways for exposure to metals is drinking water ingestion. Chronic or acute exposure to metals can endanger the health of the exposed population, and hence, estimation of human health risks is crucial. In the current study for the first time, the concentrations of Mercury (Hg), Arsenic (As), Zinc (Zn), Lead (Pb) and Cobalt (Co) in 120 collected tap water samples (2015, July-November) from Ilam city, Iran were investigated using flame atomic absorption spectrophotometer. Also, the metal-induced carcinogenic and non-carcinogenic risks for consumers exposed to tap drinking water were calculated. The average (range) concentrations of Hg, Zn, As, Pb and Co were defined as 0.40 ± 0.10 μg/L (ND-0.9 μg/L), 5014 ± 5707 μg/L (2900.00-5668.33 μg/L), 21.008 ± 2.876 μg/L (3.5-62 μg/L), 30.38 ± 5.56 μg/L (6-87 μg/L), and 11.34 ± 1.61 μg/L (0.1-50 μg/L), respectively. Average concentrations of all examined metals were significantly higher than WHO and national standard recommended limits. The ranking order of metals concentrations in the tap drinking water was Zn > Pb > As > Co > Hg. Except for Hg and Co, at least one age group consumers were at considerable non-carcinogenic risks induced by Zn, As and Pb [Target Hazard Quotient (THQ > 1)]. The rank order of age groups consumers based on THQ and Incremental lifetime cancer risk (ILCR) was <1 years >1-9 years > 20 + years > 10-19 years. The calculated ILCR for As in all age groups were higher than 10 value. All age groups of consumers in Ilam city, especially infants (<1 years) and children (1-10 years), are at considerable non-carcinogenic and carcinogenesis risk.

摘要

饮用水摄入是暴露于金属的最重要途径之一。慢性或急性暴露于金属会危害暴露人群的健康,因此,估计人类健康风险至关重要。在目前的研究中,首次使用火焰原子吸收分光光度计调查了 2015 年 7 月至 11 月从伊朗伊拉姆市采集的 120 个自来水样本中汞(Hg)、砷(As)、锌(Zn)、铅(Pb)和钴(Co)的浓度。此外,还计算了消费者暴露于自来水的金属诱导致癌和非致癌风险。Hg、Zn、As、Pb 和 Co 的平均(范围)浓度定义为 0.40±0.10μg/L(ND-0.9μg/L)、5014±5707μg/L(2900.00-5668.33μg/L)、21.008±2.876μg/L(3.5-62μg/L)、30.38±5.56μg/L(6-87μg/L)和 11.34±1.61μg/L(0.1-50μg/L)。所有检测金属的平均浓度均明显高于世界卫生组织和国家标准推荐限值。自来水中金属浓度的排序顺序为 Zn>Pb>As>Co>Hg。除 Hg 和 Co 外,至少一个年龄组消费者因 Zn、As 和 Pb 而面临相当大的非致癌风险[目标危害系数(THQ>1)]。基于 THQ 和增量终生癌症风险(ILCR)的消费者年龄组排序为<1 岁>1-9 岁>20+岁>10-19 岁。所有年龄组消费者的 As 计算 ILCR 均高于 10 值。伊拉姆市所有年龄段的消费者,尤其是婴儿(<1 岁)和儿童(1-10 岁),都面临相当大的非致癌和致癌风险。

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