Department of Radiology and Diagnostic Imaging, University of California, San Francisco 505 Parnassus Avenue, Room L352, San Francisco, CA 94143-0628, United States.
Department of Radiology and Diagnostic Imaging, University of California, San Francisco 505 Parnassus Avenue, Room L352, San Francisco, CA 94143-0628, United States.
Neuroimage. 2019 Jan 15;185:793-801. doi: 10.1016/j.neuroimage.2018.04.044. Epub 2018 Apr 22.
Pediatric neuroimaging is challenging due the rapid structural, metabolic, and functional changes that occur in the developing brain. A specially trained team is needed to produce high quality diagnostic images in children, due to their small physical size and immaturity. Patient motion, cooperation and medical condition dictate the methods and equipment used. A customized approach tailored to each child's age and functional status with the appropriate combination of dedicated staff, imaging hardware, and software is key; these range from low-tech techniques, such as feed and swaddle, to specialized small bore MRI scanners, MRI compatible incubators and neonatal head coils. New pre-and post-processing techniques can also compensate for the motion artifacts and low signal that often degrade neonatal scans.
儿科神经影像学具有挑战性，因为在发育中的大脑中会发生快速的结构、代谢和功能变化。由于儿童的身体较小且不成熟，因此需要一支经过专门培训的团队来生成高质量的诊断图像。患者的运动、配合和身体状况决定了所使用的方法和设备。根据每个孩子的年龄和功能状态，采用适当的专业人员、成像硬件和软件组合来定制个性化的方法是关键；这些方法包括从低技术技术，如喂食和襁褓，到专门的小口径 MRI 扫描仪、MRI 兼容培养箱和新生儿头部线圈。新的预处理和后处理技术也可以弥补经常降低新生儿扫描质量的运动伪影和低信号。
