Mirtha Listya Tresnanti, Permatahati Viandini
Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Acta Med Indones. 2018 Jan;50(1):82-87.
peripheral neuropathy is known as one of most common complication in diabetes mellitus type 2 patient. This complication is caused by uncontrolled condition of blood glucose level in long periode. Regular physical activity in moderate to high intensity is beneficial in management of diabetes mellitus. This report aimed to know the effectiveness of aerobic exercise in causing improved peripheral functions in type 2 diabetes mellitus.
literature searching using several related keywords in Medline®, Pubmed®, and Cochrane library, following inclusion and exclusion criteria.
Dixit et al suggested that a heart rate intensity of 40-60% aerobic exercise of 30-45 min duration per session for eight weeks suggest an important impact in controlling diabetic peripheral neuropathy. Kluding PM et al suggested that significantly improved selected measures of peripheral nerve function ("worst" pain levels and MNSI score), glycemic control (HbA1c), and resting heart rate.
the studies showed significant benefit of aerobic exercise, despite the short duration of exercise being used as intervention towards improvement in peripheral nerve function. However, further studies with large samples and longer duration of intervention are needed to confirm the finding.
周围神经病变是2型糖尿病患者最常见的并发症之一。这种并发症是长期血糖水平控制不佳所致。中等至高强度的规律体育活动对糖尿病的管理有益。本报告旨在了解有氧运动对改善2型糖尿病患者周围神经功能的有效性。
按照纳入和排除标准，在医学索引数据库（Medline®）、美国国立医学图书馆医学期刊数据库（Pubmed®）和考克兰图书馆中使用多个相关关键词进行文献检索。
迪克西特等人指出，每次有氧运动持续30 - 45分钟，心率强度为40 - 60%，共进行八周，对控制糖尿病周围神经病变有重要影响。克鲁丁等人指出，周围神经功能的选定指标（“最严重”疼痛程度和密歇根神经病变筛查指数评分）、血糖控制（糖化血红蛋白）和静息心率有显著改善。
这些研究表明有氧运动有显著益处，尽管作为干预措施的运动持续时间较短，但仍能改善周围神经功能。然而，需要进一步开展大样本、长时间干预的研究来证实这一发现。
