Lefevre Cassandra, Mallett Lea H, Wick Lori
Department of Pediatrics, Texas A&M Health Science Center, McLane Children's Medical Center, Baylor Scott & White Health, Temple, Texas.
Proc (Bayl Univ Med Cent). 2018 Feb 1;31(1):51-52. doi: 10.1080/08998280.2017.1401343. eCollection 2018 Jan.
Thiamine (vitamin B1) is an essential vitamin found in most food products in developed nations. Deficiencies in this crucial vitamin lead to diseases related to nutritional needs, metabolic demands, enzymatic function, and neurological inflammation. We present an 18-year-old patient with a history of nasopharyngeal carcinoma and total parenteral nutrition (TPN) dependence who experienced neurological manifestations and heart failure, likely due to underlying thiamine deficiency, dehydration, and vasodilation. The patient exhibited heart failure due to thiamine deficiency that was overlooked by her care team secondary to a reaction to preservatives associated with vitamins in TPN, lapse in communication, and decreased compliance.
硫胺素（维生素B1）是一种必需维生素，在发达国家的大多数食品中都能找到。这种关键维生素的缺乏会导致与营养需求、代谢需求、酶功能和神经炎症相关的疾病。我们报告一名18岁的患者，有鼻咽癌病史且依赖全胃肠外营养（TPN），该患者出现了神经症状和心力衰竭，可能是由于潜在的硫胺素缺乏、脱水和血管扩张所致。该患者因硫胺素缺乏而出现心力衰竭，但由于对TPN中与维生素相关的防腐剂的反应、沟通失误以及依从性下降，其护理团队忽视了这一点。
