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[简明纳米医学综述]

[CONCISE NANOMEDICINE REVIEW].

作者信息

Haddad Menashe, Popovtzer Rachela, Yariv Inbar, Motiei Menachem, Fixler Dror

机构信息

Sackler Faculty of Medicine, Tel-Aviv University.

Mayanei Hayeshua Medical Center.

出版信息

Harefuah. 2018 Apr;157(4):232-236.

Abstract

Nanomedicine is a rapidly evolving medical domain utilizing 1-100nm nanoscale particles to achieve medical goals in either one or more medical aspects - diagnosis, imaging and therapy. Nanomedicine employs a combination of methods stemming from life and exact sciences. This review deals briefly with the principles behind the scenes guiding the design, manufacture and employment of these nanoparticles. Some representative examples of the various applications are provided from the abundance of existing nanoparticles. The main topics discussed are those related to composition, characteristics of nanoparticles, usage in cancer, drug delivery and various central nervous system applications. Possible toxicity and future teratogenicity research pertaining to nanoparticles are also elaborated upon.

摘要

纳米医学是一个快速发展的医学领域,它利用1-100纳米的纳米级颗粒在一个或多个医学方面——诊断、成像和治疗——实现医学目标。纳米医学采用了源于生命科学和精密科学的多种方法。本综述简要介绍了指导这些纳米颗粒设计、制造和应用的幕后原理。从大量现有的纳米颗粒中提供了各种应用的一些代表性例子。讨论的主要主题是与纳米颗粒的组成、特性、在癌症中的应用、药物递送以及各种中枢神经系统应用相关的主题。还阐述了与纳米颗粒相关的可能的毒性和未来致畸性研究。

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