Kośmider Leon, Madej Daria, Gawron Michał, Sobczak Andrzej
Przegl Lek. 2016;73(10):699-703.
E-cigarette (EC) was designed to provide less harmful alternative to conventional cigarettes. Along with growing popularity of ECs around the world, more products have appeared on the market. There are limited safety studies and data relating to potential toxicity of EC use. Therefore, there is strong need to gain thorough information about a composition of generated aerosol from ECs. Due to the fact that ECs settings and puffing regimes influence vapor and toxins generation, we decided to identify parameters that have the greatest impact on the aerosol yield.
We took into account three puffing parameters: puff volume, puff duration and interpuff interval. The study was divided into two stages. In a first stage puffing regimes were achieved in testing volunteers (14 men and 11 women). In a second one found parameters (volume, puffs durations, intervals between puffs) were used to mimic ECs use in laboratory settings to examine influence of different puffing regimes on aerosol yields. Smoking machine was used to generate aerosol (6 times for each set of parameters). Aerosol yield was represented as amount of e-liquid trapped on Cambridge filter.
The results of puffing regimes study among ECs users are presented as mean ± SD: puff volume [mL] 65 ± 49, puff duration [s] 2.8 ± 2.7 and intervals between puffs [s] 16 ± 40. Aerosol yields varied depending on the set puffing regimes.
Our results indicate that the most important puffing parameters, which determine aerosol yield, are puffs duration and interpuff intervals. Puffs volume (between 41- 76 mL) has no influence on aerosol yield.
电子烟（EC）旨在提供比传统香烟危害更小的替代品。随着电子烟在全球范围内越来越受欢迎，市场上出现了更多产品。关于电子烟使用潜在毒性的安全性研究和数据有限。因此，迫切需要全面了解电子烟产生的气溶胶成分。由于电子烟的设置和抽吸方式会影响蒸汽和毒素的产生，我们决定确定对气溶胶产量影响最大的参数。
我们考虑了三个抽吸参数：抽吸量、抽吸持续时间和抽吸间隔时间。该研究分为两个阶段。在第一阶段，在测试志愿者（14名男性和11名女性）中实现抽吸方式。在第二阶段，使用找到的参数（体积、抽吸持续时间、抽吸间隔）在实验室环境中模拟电子烟使用，以检查不同抽吸方式对气溶胶产量的影响。使用吸烟机产生气溶胶（每组参数重复6次）。气溶胶产量以捕获在剑桥滤纸上的电子烟液量表示。
电子烟使用者抽吸方式研究的结果以平均值±标准差表示：抽吸量[mL]65±49，抽吸持续时间[s]2.8±2.7，抽吸间隔时间[s]16±40。气溶胶产量因设定的抽吸方式而异。
我们的结果表明，决定气溶胶产量的最重要抽吸参数是抽吸持续时间和抽吸间隔时间。抽吸量（41 - 76 mL之间）对气溶胶产量没有影响。
