1 Department of Women's and Children's Health, Clinical Psychology in Healthcare, Uppsala University, Sweden.
2 Department of Medical Sciences: Cardiology, Uppsala Clinical Research Centre, Uppsala University, Sweden.
Eur J Prev Cardiol. 2018 Jun;25(9):910-920. doi: 10.1177/2047487318770510. Epub 2018 Apr 25.
Background Emotional distress, symptoms of depression and anxiety, is common among patients after a myocardial infarction (MI), and is associated with an increased risk of cardiovascular morbidity. Real world population data on factors associated with emotional distress in MI patients are scarce. The aim was to determine factors associated with incident emotional distress two and 12 months post MI respectively, and with persistent emotional distress, versus remittent, in patients <75 years old. Design This was a registry-based observational study. Methods Data from the national SWEDEHEART registry on 27,267 consecutive patients with a first-time MI, followed up at two and 12 months post MI ( n = 22,911), were included in the analyses. Emotional distress was assessed with the EuroQol-5D questionnaire. Several candidate sociodemographic and clinical factors were analysed for their association with emotional distress in multivariate models. Results Symptoms of emotional distress were prevalent in 38% and 33% at two and 12 months post MI respectively. At both time-points, previous depression and/or anxiety, readmission for new cardiovascular event, female gender, younger age, born outside the neighbouring Nordic countries, smoking and being neither employed nor retired showed the strongest associations with emotional distress. Other factors related to medical history, the MI and its care or were only modestly associated with emotional distress. Persistent emotional distress was associated with younger age, female gender, smoking and being born outside of the Nordic countries. Conclusion Previous depression/anxiety, female gender, younger age, smoking, born outside of the Nordic countries, neither employed nor retired and readmission due to cardiovascular events were strongly associated with emotional distress post MI. These factors may be of relevance in tailoring rehabilitation programmes.
心肌梗死后(MI)患者常出现情绪困扰、抑郁和焦虑症状,这与心血管发病率增加有关。MI 患者情绪困扰相关因素的真实世界人群数据较为匮乏。本研究旨在分别确定 MI 后 2 个月和 12 个月时发生情绪困扰的相关因素,以及与持续情绪困扰(而非缓解)相关的因素,纳入年龄<75 岁的患者。
这是一项基于登记的观察性研究。
纳入全国 SWEDEHEART 登记处的 27267 例首次 MI 连续患者的数据,对其进行 MI 后 2 个月和 12 个月的随访(n=22911)。使用欧洲五维健康量表(EQ-5D)评估情绪困扰。对多个候选社会人口学和临床因素进行分析,以确定其与情绪困扰的多变量相关性。
分别有 38%和 33%的患者在 MI 后 2 个月和 12 个月时出现情绪困扰症状。在这两个时间点,既往抑郁和/或焦虑、因新发心血管事件再次入院、女性、年龄较小、出生于北欧以外国家、吸烟和既未就业也未退休与情绪困扰的相关性最强。与既往病史、MI 及其治疗相关的其他因素与情绪困扰的相关性仅为中度。持续的情绪困扰与年龄较小、女性、吸烟、出生于北欧以外国家、既未就业也未退休以及因心血管事件再次入院相关。
既往抑郁/焦虑、女性、年龄较小、吸烟、出生于北欧以外国家、既未就业也未退休以及因心血管事件再次入院与 MI 后情绪困扰密切相关。这些因素可能与康复计划的制定相关。