Mnatsakanyan Lilit, Vadera Sumeet, Ingalls Christopher W, Zheng Jie, Sazgar Mona, Hsu Frank P, Lin Jack J
Department of Neurology, University Of California, Irvine, United States.
Department of Neurological Surgery, University of California, Irvine, United States.
Epilepsy Behav Case Rep. 2017 Jun 17;9:42-45. doi: 10.1016/j.ebcr.2017.06.002. eCollection 2018.
Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, patients are excluded from surgery. We present a patient with drug-resistant frontal lobe epilepsy who underwent successful surgery with resection of Broca's area, primarily involving the pars triangularis (BA 45). We report transient expressive aphasia followed by recovery of speech. This case provides new insights into adult neuroplasticity of the language network.
癫痫手术适用于特定的药物难治性局灶性癫痫患者。癫痫手术的预期目标是实现无癫痫发作或显著减轻癫痫发作负担，同时不冒出现新的神经功能缺损的风险。通常，当癫痫发作起始区与明确的皮层区域重叠时，患者会被排除在手术之外。我们报告了一名患有药物难治性额叶癫痫的患者，该患者成功接受了手术，切除了主要涉及三角部（BA 45）的布洛卡区。我们报告了术后出现短暂的表达性失语，随后言语功能恢复。该病例为语言网络的成人神经可塑性提供了新的见解。
